Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | APEX1 | P27695 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20225318 | 0.99 | ALDH1A1 (0.56) | ALDH1A1LMNAALOX15APEX1MAPK1 | |
| SCHEMBL24260590 | 0.95 | ALDH1A1 (0.57) | ALDH1A1LMNAALOX15APEX1MAPK1 | |
| SCHEMBL23188134 | 0.90 | ALDH1A1 (0.55) | ALDH1A1LMNAALOX15APEX1MAPK1 | |
| SCHEMBL9809349 | 0.84 | MEN1 (0.50) | ALDH1A1MEN1KMT2AHTTNPC1 | |
| SCHEMBL7100665 | 0.84 | ALDH1A1 (0.63) | ALDH1A1LMNAALOX15APEX1MAPK1 | |
| SCHEMBL20225323 | 0.83 | HDAC3 (0.47) | ALDH1A1MAPTMEN1KMT2AEPHX2 | |
| SCHEMBL541916 | 0.80 | CES2 (0.54) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL24719139 | 0.79 | ALDH1A1 (0.53) | ALDH1A1LMNAALOX15APEX1MAPK1 | |
| SCHEMBL9440242 | 0.78 | HTT (0.52) | ALDH1A1LMNAMEN1KMT2AHTT | |
| SCHEMBL27457534 | 0.78 | HTT (0.52) | ALDH1A1LMNAMEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7446230-B2 | Dibenzoylmethane-based compounds, use as photoactivatable sunscreens and cosmetic compositions containing them | LABORATOIRE BIODERMA (FR) | 2008-11-04 | — | — | US | claimed |
| US-20070025930-A1 | Dibenzoilmethane derivative compounds, the use thereof in the form of photoactivable solar filters and cosmetic compositions containing said compounds | UNIVERSITE PAUL SABATIER TOULOUSE 3 (FR) | 2007-02-01 | — | — | US | claimed |
| US-7446230-B2 | Dibenzoylmethane-based compounds, use as photoactivatable sunscreens and cosmetic compositions containing them | LABORATOIRE BIODERMA (FR) | 2008-11-04 | — | — | US | disclosed |
| US-7446230-B2 | Dibenzoylmethane-based compounds, use as photoactivatable sunscreens and cosmetic compositions containing them | LABORATOIRE BIODERMA (FR) | 2008-11-04 | — | — | US | disclosed |
| US-20070025930-A1 | Dibenzoilmethane derivative compounds, the use thereof in the form of photoactivable solar filters and cosmetic compositions containing said compounds | UNIVERSITE PAUL SABATIER TOULOUSE 3 (FR) | 2007-02-01 | — | — | US | disclosed |
| US-20070025930-A1 | Dibenzoilmethane derivative compounds, the use thereof in the form of photoactivable solar filters and cosmetic compositions containing said compounds | UNIVERSITE PAUL SABATIER TOULOUSE 3 (FR) | 2007-02-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070025930-A1 | Dibenzoilmethane derivative compounds, the use thereof in the form of photoactivable solar filters and cosmetic compositions containing said compounds | TYR, DSG1, DPM1 | ALDH1A1 227/4885LMNA 689/4885ALOX15 988/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.