SCHEMBL7100665

SCHEMBL7100665

CCC(C(=O)c1ccc(OC)cc1)C(=O)c1ccc(C(C)(C)C)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.63
LMNA P02545 5/20 0.63
TDP1 Q9NUW8 2/20 0.63
ALOX15 P16050 1/20 0.63
APEX1 P27695 1/20 0.63
MAPK1 P28482 1/20 0.63
RECQL P46063 1/20 0.63
HSD17B10 Q99714 1/20 0.63
MAPT P10636 3/20 0.60
MEN1 O00255 3/20 0.56
KMT2A Q03164 3/20 0.56
NPC1 O15118 1/20 0.56
EPHX2 P34913 1/20 0.56
RAB9A P51151 1/20 0.56
NR1H4 Q96RI1 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
SLC2A1 P11166 1/20 0.49
HTT P42858 3/20 0.48
KDM4E B2RXH2 2/20 0.48
SMN1; SMN2 Q16637 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5217775 0.89 GSK3B (0.56) ALDH1A1LMNAMEN1KMT2ASLC2A1
SCHEMBL10933232 0.86 ACHE (0.52) ALDH1A1LMNATDP1ALOX15APEX1
SCHEMBL24260590 0.86 ALDH1A1 (0.57) ALDH1A1LMNATDP1ALOX15APEX1
SCHEMBL20225318 0.85 ALDH1A1 (0.56) ALDH1A1LMNATDP1ALOX15APEX1
SCHEMBL4853025 0.84 ALDH1A1 (0.55) ALDH1A1LMNATDP1ALOX15APEX1
SCHEMBL9353462 0.83 MAPT (0.66) ALDH1A1LMNATDP1ALOX15APEX1
SCHEMBL7733638 0.83 MAPT (0.66) ALDH1A1LMNATDP1ALOX15APEX1
SCHEMBL2290396 0.82 ALDH1A1 (0.60) ALDH1A1MAPTMEN1KMT2ANPC1
SCHEMBL23188134 0.81 ALDH1A1 (0.55) ALDH1A1LMNATDP1ALOX15APEX1
SCHEMBL14435692 0.80 LDHA (0.50) ALDH1A1LMNATDP1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1280505-A1 PHOTOSTABILIZATION OF DIBENZOYLMETHANE DERIVATIVES Ciba SC Holding AG (CH) 2003-02-05 EP disclosed
WO-2001085123-A1 PHOTOSTABILIZATION OF DIBENZOYLMETHANE DERIVATIVES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2001-11-15 WO disclosed