Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.49 |
| ▸ | NAMPT | P43490 | 2/20 | 0.48 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.47 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.47 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.47 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.47 |
| ▸ | GLS | O94925 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.46 |
| ▸ | CSF1R | P07333 | 2/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.43 |
| ▸ | KIT | P10721 | 1/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.43 |
| ▸ | FLT3 | P36888 | 1/20 | 0.43 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.43 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14306286 | 0.85 | TRPV1 (0.51) | TRPV1NAMPTKCNQ3KCNQ2KCNQ4 | |
| SCHEMBL30791579 | 0.85 | TRPV1 (0.51) | TRPV1NAMPTKCNQ3KCNQ2KCNQ4 | |
| SCHEMBL22501639 | 0.83 | TRPV1 (0.52) | TRPV1NAMPTKCNQ3KCNQ2KCNQ4 | |
| SCHEMBL19318505 | 0.82 | PTGES (0.55) | TRPV1NAMPTKCNQ3KCNQ2KCNQ4 | |
| SCHEMBL31236179 | 0.82 | TRPV1 (0.51) | TRPV1NAMPTKCNQ3KCNQ2KCNQ4 | |
| SCHEMBL27778348 | 0.82 | RIPK1 (0.55) | TRPV1NAMPTKCNQ3KCNQ2KCNQ4 | |
| SCHEMBL14279029 | 0.81 | PTGES (0.56) | TRPV1NAMPTKCNQ3KCNQ2KCNQ4 | |
| SCHEMBL30074796 | 0.79 | TRPV1 (0.52) | TRPV1NAMPTKCNQ3KCNQ2KCNQ4 | |
| SCHEMBL28907319 | 0.79 | TRPV1 (0.52) | TRPV1NAMPTKCNQ3KCNQ2KCNQ4 | |
| SCHEMBL10263975 | 0.79 | L3MBTL1 (0.50) | TRPV1NAMPTKCNQ3KCNQ2KCNQ4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070254867-A1 | Heterocyclic Kinase Inhibitors | ABBVIE INC. | 2007-11-01 | — | — | US | claimed |
| US-20040254159-A1 | Heterocyclic kinase inhibitors | ABBOTT LABORATORIES | 2004-12-16 | — | — | US | claimed |
| CN-118561801-A | Benzo [ d ] [1,3] dioxoles compound, preparation method and application thereof | 上海医药集团股份有限公司 | 2024-08-30 | — | — | CN | disclosed |
| US-7456169-B2 | Heterocyclic kinase inhibitors | ABBOTT LABORATORIES INC. (US) | 2008-11-25 | — | — | US | disclosed |
| US-20070254867-A1 | Heterocyclic Kinase Inhibitors | ABBVIE INC. | 2007-11-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040254159-A1 | Heterocyclic kinase inhibitors | MAP3K20, MAP3K19, MAP3K1 | TRPV1 4626/4885NAMPT 1330/4885KCNQ3 3070/4885 |
| US-20070254867-A1 | Heterocyclic Kinase Inhibitors | MAP3K20, MAP3K19, MAP4K2 | TRPV1 4559/4885NAMPT 1036/4885KCNQ3 3066/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.