Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOS | P01100 | 2/20 | 0.48 |
| ▸ | JUN | P05412 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | THRA | P10827 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.43 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4281226 | 0.88 | MAPK1 (0.42) | FOSJUNMAPK1THRATHRB | |
| SCHEMBL4281229 | 0.88 | MAPK1 (0.42) | FOSJUNMAPK1THRATHRB | |
| SCHEMBL4277956 | 0.88 | CYP19A1 (0.44) | FOSJUNMAPK1LTB4RPLA2G2D | |
| SCHEMBL4289851 | 0.83 | LMNA (0.46) | FOSJUNMAPK1THRATHRB | |
| SCHEMBL4280876 | 0.82 | THRA (0.47) | MAPK1THRATHRBXDHHTT | |
| SCHEMBL4277069 | 0.81 | FOS (0.40) | FOSJUNMAPK1THRATHRB | |
| SCHEMBL4279655 | 0.81 | FOS (0.56) | FOSJUNMAPK1THRATHRB | |
| SCHEMBL4276633 | 0.81 | MAPK1 (0.64) | MAPK1XDHHTTPOLBCASP6 | |
| SCHEMBL4276406 | 0.80 | ALDH1A1 (0.43) | FOSJUNMAPK1THRATHRB | |
| SCHEMBL4276411 | 0.80 | ALDH1A1 (0.43) | FOSJUNMAPK1THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7314888-B1 | Compounds and medicinal use thereof | TOYAMA CHEMICAL CO., LTD. (JP) | 2008-01-01 | — | — | US | disclosed |
| EP-1127869-A1 | NOVEL COMPOUNDS AND MEDICINAL USE THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 2001-08-29 | — | — | EP | disclosed |