Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.52 |
| ▸ | IDO1 | P14902 | 2/20 | 0.50 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.50 |
| ▸ | BCL2 | P10415 | 1/20 | 0.46 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.46 |
| ▸ | CTRC | Q99895 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL28195073 | 0.98 | HTR2A (0.56) | HTR2ATAAR1IDO1CALM1BCL2 | |
| SCHEMBL423302 | 0.98 | HTR2A (0.56) | HTR2ATAAR1IDO1CALM1BCL2 | |
| Fluoride SCHEMBL27939369 | 0.95 | HTR2A (0.54) | HTR2ATAAR1IDO1CALM1BCL2 | |
| SCHEMBL28517240 | 0.89 | HTR2A (0.48) | HTR2ATAAR1IDO1CALM1BCL2 | |
| Boric Acid SCHEMBL28279493 | 0.89 | HTR2A (0.48) | HTR2ATAAR1IDO1CALM1BCL2 | |
| SCHEMBL25625114 | 0.85 | TAAR1 (0.50) | HTR2ATAAR1IDO1 | |
| SCHEMBL28025161 | 0.82 | CALM1 (0.46) | HTR2ATAAR1IDO1CALM1BCL2 | |
| SCHEMBL31152647 | 0.82 | CALM1 (0.46) | HTR2ATAAR1IDO1CALM1BCL2 | |
| SCHEMBL8703610 | 0.82 | TAAR1 (0.64) | TAAR1IDO1 | |
| SCHEMBL29930048 | 0.82 | TAAR1 (0.64) | TAAR1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7459555-B2 | Photochromic naphthopyrans | RODENSTOCK GMBH (DE) | 2008-12-02 | — | — | US | disclosed |
| US-20020052499-A1 | Photochromic naphthopyrans | OPTISCHE WERKE G. RODENSTOCK | 2002-05-02 | — | — | US | disclosed |
| US-6342459-B1 | PHOTOCHROMIC COMPOUNDS AND ARTICLES OF RESIN FOR OPTHTHALMIC LENSES | OPTISCHE WERKE G. RODENSTOCK (DE) | 2002-01-29 | — | — | US | disclosed |
| US-6331625-B1 | EYEGLASS LENSES; RAPID COLOR AND BRIGHTNESS ADJUSTMENT | OPTISCHE WERKE G. RODENSTOCK (DE) | 2001-12-18 | — | — | US | disclosed |
| US-6225466-B1 | FOR ARTICLES MADE OF SYNTHETIC RESIN MATERIALS; RAPID DARKENING AND BRIGHTENING RATES, DURABILITY | OPTISCHE WERKE G. RODENSTOCK (DE) | 2001-05-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020052499-A1 | Photochromic naphthopyrans | BPNT1, NR2E3, BRIX1 | HTR2A 2489/4885TAAR1 3314/4885IDO1 1716/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.