SCHEMBL28025161

SCHEMBL28025161

Brc1cccc(Cc2ccccc2)c1Br

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CALM1 P0DP23 1/20 0.46
HTR2A P28223 1/20 0.45
BCL2 P10415 1/20 0.43
BCL2L1 Q07817 1/20 0.43
CTRC Q99895 1/20 0.43
TAAR1 Q96RJ0 2/20 0.39
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
ALOX5 P09917 1/20 0.38
GABRA1 P14867 1/20 0.38
GABRB2 P47870 1/20 0.38
HPGD P15428 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
IDO1 P14902 1/20 0.38
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
LOXL2 Q9Y4K0 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31152647 1.00 CALM1 (0.46) CALM1HTR2ABCL2BCL2L1CTRC
SCHEMBL4872180 0.89 CALM1 (0.52) CALM1HTR2ABCL2BCL2L1CTRC
SCHEMBL9016954 0.86 GABRA1 (0.48) TAAR1CYP1A2CYP2D6CYP2C19GABRA1
Benzene SCHEMBL28195073 0.84 HTR2A (0.56) CALM1HTR2ABCL2BCL2L1CTRC
SCHEMBL423302 0.84 HTR2A (0.56) CALM1HTR2ABCL2BCL2L1CTRC
SCHEMBL31152648 0.83 CTRC (0.47) CALM1HTR2ABCL2BCL2L1CTRC
SCHEMBL4853233 0.82 HTR2A (0.54) CALM1HTR2ABCL2BCL2L1CTRC
Fluoride SCHEMBL27939369 0.82 HTR2A (0.54) CALM1HTR2ABCL2BCL2L1CTRC
SCHEMBL10504623 0.81 ALDH1A1 (0.50) TAAR1CYP3A4CYP2C19GABRA1GABRB2
SCHEMBL3667640 0.81 CALM1 (0.44) CALM1HTR2ABCL2BCL2L1CTRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024230246-A1 POLYPEPTIDE RADIONUCLIDE COMPLEX TARGETING FIBROBLAST ACTIVATION PROTEIN AND USE THEREOF 成都纽瑞特医疗科技股份有限公司 2024-11-14 WO claimed
CN-104716352-A Use of crosslinking type polybenzimidazole porous separating membrane in liquid flow battery DALIAN CHEMICAL PHYSICS INST 2015-06-17 CN claimed
WO-2024230246-A1 POLYPEPTIDE RADIONUCLIDE COMPLEX TARGETING FIBROBLAST ACTIVATION PROTEIN AND USE THEREOF 成都纽瑞特医疗科技股份有限公司 2024-11-14 WO disclosed
CN-109803992-B Isocyanate composition and method for producing isocyanate polymer 旭化成株式会社 2022-05-24 CN disclosed
CN-109843963-B Isocyanate composition, method for producing isocyanate polymer, and isocyanate polymer 旭化成株式会社 2022-05-13 CN disclosed
CN-104716352-A Use of crosslinking type polybenzimidazole porous separating membrane in liquid flow battery DALIAN CHEMICAL PHYSICS INST 2015-06-17 CN disclosed