SCHEMBL4853279

SCHEMBL4853279

[CH2]CC(=O)OCCOCC

nearest known ligand 0.58

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.58
TSHR P16473 3/20 0.58
THRB P10828 2/20 0.55
DGKA P23743 1/20 0.39
HSD17B10 Q99714 4/20 0.38
MGAM O43451 1/20 0.37
GAA P10253 1/20 0.37
SI P14410 1/20 0.37
MGAM2 Q2M2H8 1/20 0.37
TP53 P04637 2/20 0.37
HIF1A Q16665 2/20 0.37
EPHX2 P34913 1/20 0.35
TRPA1 O75762 1/20 0.34
NAAA Q02083 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.33
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4848165 0.98 ALDH1A1 (0.56) ALDH1A1TSHRTHRBDGKAHSD17B10
SCHEMBL8195672 0.84 DGKA (0.42) ALDH1A1TSHRTHRBDGKAHSD17B10
SCHEMBL4856120 0.83 ALDH1A1 (0.54) ALDH1A1TSHRTHRBDGKAHSD17B10
SCHEMBL1799780 0.83 DGKA (0.39) ALDH1A1TSHRTHRBDGKAHSD17B10
SCHEMBL106760 0.81 ALDH1A1 (0.62) ALDH1A1TSHRTHRBDGKAHSD17B10
SCHEMBL9598368 0.81 ALDH1A1 (0.62) ALDH1A1TSHRTHRBDGKAHSD17B10
SCHEMBL1301905 0.81 ALDH1A1 (0.62) ALDH1A1TSHRTHRBDGKAHSD17B10
SCHEMBL8195957 0.81
SCHEMBL4849689 0.81 ALDH1A1 (0.52) ALDH1A1TSHRTHRBDGKAHSD17B10
SCHEMBL8894704 0.81 DGKA (0.48) ALDH1A1TSHRTHRBDGKAHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0684287-A1 Water insoluble red monoazo dyes, their preparation and the use thereof HOECHST MITSUBISHI KASEI CO., LTD. (JP) 1995-11-29 EP claimed
US-5283326-A Coupling azo and cyanine dyes; colorfastness, heat resistance SANDOZ AG (CH) 1994-02-01 US claimed
US-4960873-A 3-pyridylisothiazoleazo compounds useful as disperse dyes BASF AKTIENGESELLSCHAFT (DE) 1990-10-02 US claimed
US-4837269-A FIBER-REACTIVE DISAZO DYES BASF AKTIENGESELLSCHAFT (DE) 1989-06-06 US claimed
US-4751288-A COLORFASTNESS BASF AKTIENGESELLSCHAFT (DE) 1988-06-14 US claimed
US-4619992-A IMPROVED COLORFASTNESS BASF AKTIENGESELLSCHAFT (DE) 1986-10-28 US claimed
US-4496480-A Isothiazolazo dyes having coupling components which are free from unsaturated aliphatic radicals BASF AKTIENGESELLSCHAFT (DE) 1985-01-29 US claimed
US-20190171099-A1 POLYMERIZABLE COMPOSITION COMPRISING AN OXIME SULFONATE AS THERMAL CURING AGENT BASF SE (DE) 2019-06-06 US disclosed
US-10241399-B2 Polymerizable composition comprising an oxime sulfonate as thermal curing agent BASF SE (DE) 2019-03-26 US disclosed
EP-2668156-B1 POLYMERIZABLE COMPOSITION COMPRISING AN OXIME SULFONATE AS THERMAL CURING AGENT BASF SE (DE) 2018-10-31 EP disclosed
US-9310677-B2 Polymerizable composition comprising an oxime sulfonate as thermal curing agent BASF (DE) 2016-04-12 US disclosed
US-20160060214-A1 POLYMERIZABLE COMPOSITION COMPRISING AN OXIME SULFONATE AS THERMAL CURING AGENT BASF SE (DE) 2016-03-03 US disclosed
EP-2668156-A1 POLYMERIZABLE COMPOSITION COMPRISING AN OXIME SULFONATE AS THERMAL CURING AGENT BASF SE (DE) 2013-12-04 EP disclosed
EP-0156216-A1 Isothiazole azo dyestuffs BASF Aktiengesellschaft (DE) 1985-10-02 EP disclosed
EP-0087677-B1 ISOTHIAZOLAZO DYESTUFFS BASF Aktiengesellschaft (DE) 1985-07-17 EP disclosed
US-4496480-A Isothiazolazo dyes having coupling components which are free from unsaturated aliphatic radicals BASF AKTIENGESELLSCHAFT (DE) 1985-01-29 US disclosed
EP-0131757-A1 Disazo dyestuffs of the isothiazole series BASF Aktiengesellschaft (DE) 1985-01-23 EP disclosed
EP-0087677-A1 Isothiazolazo dyestuffs BASF Aktiengesellschaft (DE) 1983-09-07 EP disclosed
US-4252604-A OPTICAL BRIGHTENERS SANDOZ LTD. (CH) 1981-02-24 US disclosed
US-3935183-A WATER INSOLUBLE DYE IMPERIAL CHEMICAL INDUSTRIES LIMITED (EN) 1976-01-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10241399-B2 Polymerizable composition comprising an oxime sulfonate as thermal curing agent SULT1E1, COX6B1, SULT1A1 ALDH1A1 776/4885TSHR 3974/4885THRB 1036/4885
US-20190171099-A1 POLYMERIZABLE COMPOSITION COMPRISING AN OXIME SULFONATE AS THERMAL CURING AGENT SULT1E1, COX6B1, SULT1A1 ALDH1A1 776/4885TSHR 3974/4885THRB 1036/4885
US-20160060214-A1 POLYMERIZABLE COMPOSITION COMPRISING AN OXIME SULFONATE AS THERMAL CURING AGENT SULT1E1, COX6B1, SULT1A1 ALDH1A1 776/4885TSHR 3974/4885THRB 1036/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.