Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.70 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | RXRA | P19793 | 1/20 | 0.48 |
| ▸ | RXRB | P28702 | 1/20 | 0.48 |
| ▸ | RXRG | P48443 | 1/20 | 0.48 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TACR1 | P25103 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16180051 | 0.82 | CES2 (0.73) | CES2GAARXRARXRBRXRG | |
| SCHEMBL11131496 | 0.80 | CES2 (0.47) | CES2GAARXRARXRBRXRG | |
| SCHEMBL22981333 | 0.80 | CES2 (0.70) | CES2GAARXRARXRBRXRG | |
| SCHEMBL503980 | 0.80 | CES2 (0.70) | CES2GAARXRARXRBRXRG | |
| SCHEMBL2191271 | 0.80 | CES2 (0.70) | CES2GAARXRARXRBRXRG | |
| SCHEMBL5778879 | 0.79 | CES2 (0.61) | CES2GAARXRARXRBRXRG | |
| SCHEMBL2090686 | 0.78 | CES2 (0.67) | CES2GAARXRARXRBRXRG | |
| SCHEMBL96116 | 0.78 | CES2 (0.67) | CES2GAARXRARXRBRXRG | |
| Hydrochloric Acid SCHEMBL7485970 | 0.78 | CES2 (0.67) | CES2GAARXRARXRBRXRG | |
| SCHEMBL3550111 | 0.78 | CES2 (0.67) | CES2GAARXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1125913-B1 | Preparation of 3,5-bis-(trifluormethyl)-benzoylchlorid and novel benzoylhalides: 3,5-bis-(trihalomethyl)- and 3,5-dimethyl- | BAYER AG (DE) | 2003-04-09 | — | — | EP | claimed |
| EP-1125913-A1 | Preparation of 3,5-bis-(trifluormethyl)-benzoylchlorid and novel benzoylhalides: 3,5-bis-(trihalomethyl)- and 3,5-dimethyl- | BAYER AG (DE) | 2001-08-22 | — | — | EP | claimed |
| US-7405331-B2 | High-purity (fluoroalkyl)benzene derivative and process for producing the same | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2008-07-29 | — | — | US | disclosed |
| US-20060167324-A1 | High-purity (fluoroalkyl)benzene derivative and process for producing the same | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2006-07-27 | — | — | US | disclosed |
| EP-1500641-A1 | HIGH-PURITY (FLUOROALKYL)BENZENE DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2005-01-26 | — | — | EP | disclosed |
| EP-1125913-B1 | Preparation of 3,5-bis-(trifluormethyl)-benzoylchlorid and novel benzoylhalides: 3,5-bis-(trihalomethyl)- and 3,5-dimethyl- | BAYER AG (DE) | 2003-04-09 | — | — | EP | disclosed |
| US-6420601-B2 | FREE RADICAL CHLORINATION; FLUORINATION WITH HYDROGEN FLUORIDE AND/OR ANTIMONY PENTAFLUORIDE; CONVERTING THE BENZOYL FLUORIDE TO CHLORIDE BY REACTING WITH SILICON TETRACHLORIDE IN LEWIS ACID; CHEMICAL INTERMEDIATES | BAYER AKTIENGESELLSCHAFT (DE) | 2002-07-16 | — | — | US | disclosed |
| JP-2001294551-A | METHOD FOR PRODUCING 3,5-BIS(TRIFLUOROMETHYL)BENZOYL CHLORIDE AND NEW 3,5-BIS(TRIHALOGENOMETHYL)- AND 3,5- DIMETHYLBENZOYL HALIDES | BAYER AG | 2001-10-23 | — | — | JP | disclosed |
| EP-1125913-A1 | Preparation of 3,5-bis-(trifluormethyl)-benzoylchlorid and novel benzoylhalides: 3,5-bis-(trihalomethyl)- and 3,5-dimethyl- | BAYER AG (DE) | 2001-08-22 | — | — | EP | disclosed |
| EP-1125913-A1 | Preparation of 3,5-bis-(trifluormethyl)-benzoylchlorid and novel benzoylhalides: 3,5-bis-(trihalomethyl)- and 3,5-dimethyl- | BAYER AG (DE) | 2001-08-22 | — | — | EP | disclosed |
| US-20010014759-A1 | Free radical chlorination; fluorination with hydrogen fluoride and/or antimony pentafluoride; converting the benzoyl fluoride to chloride by reacting with silicon tetrachloride in lewis acid; chemical intermediates | LANXESS DEUTSCHLAND GMBH (DE) | 2001-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010014759-A1 | Free radical chlorination; fluorination with hydrogen fluoride and/or antimony pentafluoride; converting the benzoyl fluoride to chloride by reacting with silicon tetrachloride in lewis acid; chemical intermediates | SCLY, SSB, CLIC4 | CES2 836/4885GAA 2525/4885RXRA 1091/4885 |
| US-20060167324-A1 | High-purity (fluoroalkyl)benzene derivative and process for producing the same | HBB, AFF4, AFF2 | CES2 2075/4885GAA 937/4885RXRA 1226/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.