Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.67 |
| ▸ | RXRA | P19793 | 2/20 | 0.54 |
| ▸ | RXRB | P28702 | 2/20 | 0.54 |
| ▸ | RXRG | P48443 | 2/20 | 0.54 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.49 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | PLD2 | O14939 | 1/20 | 0.43 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | TACR1 | P25103 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formaldehyde SCHEMBL459554 | 0.96 | CES2 (0.61) | CES2RXRARXRBRXRGAKR1C3 | |
| SCHEMBL12187542 | 0.92 | CES2 (0.57) | CES2RXRARXRBRXRGAKR1C3 | |
| SCHEMBL27186725 | 0.90 | CES2 (0.55) | CES2RXRARXRBRXRGAKR1C3 | |
| SCHEMBL29799797 | 0.90 | CES2 (0.55) | CES2RXRARXRBRXRGAKR1C3 | |
| SCHEMBL1198922 | 0.87 | CES2 (0.52) | CES2RXRARXRBRXRGAKR1C3 | |
| SCHEMBL31643321 | 0.87 | CA5A (0.61) | CES2RXRARXRBRXRGAKR1C3 | |
| SCHEMBL7786247 | 0.87 | CES2 (0.52) | CES2RXRARXRBRXRGAKR1C3 | |
| SCHEMBL13131605 | 0.87 | CA5A (0.61) | CES2RXRARXRBRXRGAKR1C3 | |
| SCHEMBL766077 | 0.86 | NOTUM (0.67) | CES2RXRARXRBRXRGAKR1C3 | |
| SCHEMBL4974165 | 0.86 | CES2 (0.50) | CES2RXRARXRBRXRGAKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 785 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119926191-B | Conjugated microporous organic solvent-resistant nanofiltration composite membrane and preparation method and application thereof | 中山大学 | 2025-06-13 | — | — | CN | claimed |
| CN-119926191-A | Conjugated microporous organic solvent-resistant nanofiltration composite membrane and preparation method and application thereof | 中山大学 | 2025-05-06 | — | — | CN | claimed |
| CN-118459422-A | Thiazole thiazolinone compound containing multiple halogen atoms and preparation method thereof | 南京工业大学 | 2024-08-09 | — | — | CN | claimed |
| CN-118459420-A | Thiazolinone compound containing multiple halogen atoms and preparation method thereof | 南京工业大学 | 2024-08-09 | — | — | CN | claimed |
| US-20240243010-A1 | INHIBITOR FOR SELECTIVELY DEPOSITING THIN FILM AND METHOD FOR SELECTIVELY DEPOSITING THIN FILM | ADEKA CORPORATION (JP) | 2024-07-18 | — | — | US | claimed |
| CN-115521946-B | TiO (titanium dioxide)xMethod for synthesizing (R) -1- [3, 5-di (trifluoromethyl) ] phenethyl alcohol by using base photo-enzyme catalyst | 浙江玖世生物科技有限公司 | 2024-06-21 | — | — | CN | claimed |
| CN-115386604-B | Method for catalyzing and synthesizing R-3,5-BTPE by using infrared light driven carbon quantum dot based photo-enzyme catalyst | 浙江玖世生物科技有限公司 | 2024-05-31 | — | — | CN | claimed |
| CN-114457125-B | Method for synthesizing (R) -1- [3,5-bis (trifluoromethyl) phenyl ] ethylamine by coupling transaminase and alcohol dehydrogenase | 浙江工业大学 | 2024-04-09 | — | — | CN | claimed |
| CN-117778341-A | Immobilized carbonyl reductase based on protein tag self-assembly and application of immobilized carbonyl reductase in continuous catalysis preparation of aprepitant intermediate | 浙江工业大学 | 2024-03-29 | — | — | CN | claimed |
| US-20230369039-A1 | METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2023-11-16 | — | — | US | claimed |
| EP-1409704-A2 | METHOD FOR THE ENANTIOSELECTIVE REDUCTION OF A PROCHIRAL AROMATIC KETONE COMPRISING AT LEAST ONE TRIFLUOROMETHYL GROUP ON THE AROMATIC CYCLE | RHODIA CHIMIE (FR) | 2004-04-21 | — | — | EP | claimed |
| US-20040019243-A1 | 1,3-Bis(trifluoromethyl)benzene derivatives | SYNPROTEC LIMITED (GB) | 2004-01-29 | — | — | US | claimed |
| EP-1345878-A1 | PROCESS FOR THE SYNTHESIS OF 1-(3,5-BIS(TRIFLUOROMETHYL)-PHENYL)ETHAN-1-ONE | Merck & Co., Inc. (US) | 2003-09-24 | — | — | EP | claimed |
| US-20030153760-A1 | Treating 1-(3,5- bis(trifluoromethyl)phenyl)ethan-1-one with bis((pentamethylcyclopentadienyl)rhodium chloride) and (S,R)-cis-1-amino-2-hydroxy-indane in the presence of isopropanol | MERCK & CO., INC. | 2003-08-14 | — | — | US | claimed |
| EP-1334080-A1 | 1,3-BIS(TRIFLUOROMETHYL)BENZENE DERIVATIVES | Synprotec Limited (GB) | 2003-08-13 | — | — | EP | claimed |
| WO-2003004666-A2 | METHOD FOR THE ENANTIOSELECTIVE REDUCTION OF A PROCHIRAL AROMATIC KETONE COMPRISING AT LEAST ONE TRIFLUOROMETHYL GROUP ON THE AROMATIC CYCLE | RHODIA CHIMIE (FR) | 2003-01-16 | — | — | WO | claimed |
| US-6504066-B1 | Reduction of halogen containing carbocyclic ketones, to form chemical intermediates which are substance-P receptor antagonists useful as antiinflammatory and antiemetic agents and for treatment of psychological disorders | MERCK & CO. INC. | 2003-01-07 | — | — | US | claimed |
| WO-2002050009-A1 | PROCESS FOR THE SYNTHESIS OF 1-(3,5-BIS(TRIFLUOROMETHYL)-PHENYL)ETHAN-1-ONE | MERCK & CO., INC. (US) | 2002-06-27 | — | — | WO | claimed |
| WO-2002024615-A1 | 1,3-BIS(TRIFLUOROMETHYL)BENZENE DERIVATIVES | SYNPROTEC LIMITED (GB) | 2002-03-28 | — | — | WO | claimed |
| US-6350915-B1 | FORMING A GRIGNARD REAGENT AND REACTION WITH ACETIC ANHYDRIDE | MERCK & CO., INC. | 2002-02-26 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030153760-A1 | Treating 1-(3,5- bis(trifluoromethyl)phenyl)ethan-1-one with bis((pentamethylcyclopentadienyl)rhodium chloride) and (S,R)-cis-1-amino-2-hydroxy-indane in the presence of isopropanol | HTR1D, SIGMAR1, HTR1A | CES2 772/4885RXRA 676/4885RXRB 843/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.