SCHEMBL4855046

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14513384	0.92	ALDH1A1 (0.34)	CTNNB1WNT3AALDH1A1LMNASMN1; SMN2
	SCHEMBL4860428	0.91	CTNNB1 (0.40)	CTNNB1WNT3AACHEALDH1A1LMNA
	SCHEMBL4853757	0.90	PTGS1 (0.37)	CTNNB1WNT3AACHEALDH1A1TAAR1
	SCHEMBL4861424	0.90	NPC1 (0.38)	CTNNB1WNT3AALDH1A1LMNASMN1; SMN2
	SCHEMBL5313267	0.89	ACHE (0.38)	CTNNB1WNT3AACHEPTGES2BCHE
	SCHEMBL4862735	0.89	SMN1; SMN2 (0.46)	CTNNB1ALDH1A1LMNASMN1; SMN2L3MBTL1
	SCHEMBL4859550	0.89	CTNNB1 (0.38)	CTNNB1WNT3AACHESMN1; SMN2MAPT
	SCHEMBL13987148	0.86	CTNNB1 (0.54)	CTNNB1WNT3AALDH1A1LMNASMN1; SMN2
	SCHEMBL4859871	0.85	PKM (0.43)	ACHEALDH1A1SMN1; SMN2TDP1PTGES2
	SCHEMBL13987486	0.83	TAAR1 (0.42)	CTNNB1WNT3AACHEALDH1A1TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.