Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PCSK9 | Q8NBP7 | 2/20 | 0.40 |
| ▸ | ORAI1 | Q96D31 | 3/20 | 0.38 |
| ▸ | ORAI2 | Q96SN7 | 3/20 | 0.38 |
| ▸ | ORAI3 | Q9BRQ5 | 3/20 | 0.38 |
| ▸ | TRPV6 | Q9H1D0 | 3/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5952943 | 0.83 | LPL (0.43) | ORAI1ORAI2ORAI3TRPV6 | |
| SCHEMBL1226528 | 0.79 | TRPV6 (0.44) | PCSK9ORAI1ORAI2ORAI3TRPV6 | |
| SCHEMBL4855266 | 0.74 | LMNA (0.39) | LMNAMAPTTRPA1TSHRMEN1 | |
| SCHEMBL1997852 | 0.74 | CA1 (0.50) | CA7CA14LMNAMAPTTSHR | |
| SCHEMBL5951904 | 0.73 | HTR1B (0.37) | LMNATSHRABCB1KDM4EKMT2A | |
| SCHEMBL1722636 | 0.71 | PCSK9 (0.45) | PCSK9ORAI1ORAI2ORAI3TRPV6 | |
| SCHEMBL15570627 | 0.71 | TRPV6 (0.44) | PCSK9ORAI1ORAI2ORAI3TRPV6 | |
| SCHEMBL28726874 | 0.71 | LMNA (0.42) | PCSK9ORAI1ORAI2ORAI3TRPV6 | |
| SCHEMBL28423595 | 0.71 | ENPP2 (0.39) | PCSK9ORAI1ORAI2ORAI3TRPV6 | |
| SCHEMBL18526870 | 0.71 | LMNA (0.52) | PCSK9ORAI1ORAI2ORAI3TRPV6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4715026-A1 | BORON-CONTAINING QUANTUM DOT COMPLEX AGGREGATE, PREPARATION METHOD THEREFOR, AND USE THEREOF | Cannano Jiayuan (Guangzhou) Science & Technology Co., Ltd. (CN) | 2026-03-25 | — | — | EP | disclosed |
| US-7038070-B2 | Preparation of preparing substituted indanones | BASELL POLYOLEFINE GMBH (DE) | 2006-05-02 | — | — | US | disclosed |
| US-6963017-B2 | Preparation of preparing substituted indanones | BASELL POLYOLEFINE GMBH (DE) | 2005-11-08 | — | — | US | disclosed |
| EP-0968158-B1 | METHOD OF PREPARING SUBSTITUTED INDANONES, THE SUBSTITUTED INDANONES AND METALLOCENES PREPARED THEREFROM | BASELL POLYOLEFINE GMBH (DE) | 2005-08-10 | — | — | EP | disclosed |
| US-20050033076-A1 | Preparation of preparing substituted indanones | EQUISTAR CHEMICALS, LP | 2005-02-10 | — | — | US | disclosed |
| US-20030009046-A1 | Preparation of preparing substituted indanones | EQUISTAR CHEMICALS, LP | 2003-01-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050033076-A1 | Preparation of preparing substituted indanones | CYP1A2, CYP2J2, IDH3A | PCSK9 3742/4885ORAI1 4605/4885ORAI2 1642/4885 |
| US-20030009046-A1 | Preparation of preparing substituted indanones | CYP1A2, CYP1B1, CYP1A1 | PCSK9 3869/4885ORAI1 4577/4885ORAI2 1594/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.