Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL11582714 | 0.96 | ALDH1A1 (0.50) | ALDH1A1TSHRCYP2C9HPGDMAPK1 | |
| Alcohol SCHEMBL18837465 | 0.96 | ALDH1A1 (0.50) | ALDH1A1TSHRCYP2C9HPGDMAPK1 | |
| Alcohol SCHEMBL974601 | 0.96 | ALDH1A1 (0.50) | ALDH1A1TSHRCYP2C9HPGDMAPK1 | |
| Alcohol SCHEMBL28117603 | 0.92 | ALDH1A1 (0.46) | ALDH1A1TSHRCYP2C9HPGDMAPK1 | |
| Alcohol SCHEMBL946131 | 0.89 | ALDH1A1 (0.43) | ALDH1A1TSHRCYP2C9HPGDMAPK1 | |
| Ethylene Glycol SCHEMBL5579485 | 0.87 | TSHR (0.42) | ALDH1A1TSHRCYP2C9HPGDMAPK1 | |
| Methyl Alcohol SCHEMBL341831 | 0.86 | — | — | |
| Hydrogen Peroxide SCHEMBL139129 | 0.86 | — | — | |
| Hydrogen Peroxide SCHEMBL139127 | 0.86 | ALDH1A1 (0.36) | ALDH1A1TSHRCYP2C9HPGDMAPK1 | |
| Bicarbonate SCHEMBL10783748 | 0.86 | ALDH1A1 (0.40) | ALDH1A1TSHRKDM4EMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 307 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117442601-B | Phosphatase inhibitor analogue BX-metal NPs and preparation method and application thereof | 上海市东方医院（同济大学附属东方医院） | 2024-05-28 | — | — | CN | claimed |
| CN-118067815-A | Disposable screen printing indium tin oxide electrode for rapidly detecting abnormal prothrombin, and preparation method and application thereof | 上海市浦东医院（复旦大学附属浦东医院） | 2024-05-24 | — | — | CN | claimed |
| CN-117442601-A | Phosphatase inhibitor analogue BX-metal NPs and preparation method and application thereof | 上海市东方医院（同济大学附属东方医院） | 2024-01-26 | — | — | CN | claimed |
| CN-114522737-B | Method for preparing 3-acetoxypropanol with high selectivity | 中国科学院大连化学物理研究所 | 2023-10-13 | — | — | CN | claimed |
| CN-113493392-B | Glycine-1- 14 Process for the preparation of C | 无锡贝塔医药科技有限公司 | 2023-06-02 | — | — | CN | claimed |
| CN-114045024-B | Tough wear-resistant calcium phosphate oligomer-waterborne polyurethane material and preparation method thereof | 青岛大学 | 2023-05-12 | — | — | CN | claimed |
| CN-112666269-B | Method for detecting isomer in SAR107375 by using high performance liquid chromatography | 北京联馨药业有限公司 | 2022-12-30 | — | — | CN | claimed |
| CN-114522737-A | Method for preparing 3-acetoxy propanol with high selectivity | 中国科学院大连化学物理研究所 | 2022-05-24 | — | — | CN | claimed |
| CN-114045024-A | Tough wear-resistant calcium phosphate oligomer-waterborne polyurethane material and preparation method thereof | 青岛大学 | 2022-02-15 | — | — | CN | claimed |
| CN-113493392-A | Glycine-1-14Preparation method of C | 无锡贝塔医药科技有限公司 | 2021-10-12 | — | — | CN | claimed |
| CN-106518896-A | A zinc-tetraazatricyclo complex, a preparing method thereof and applications of the complex in antitumor drugs | 南京大学 | 2017-03-22 | — | — | CN | claimed |
| CN-106281605-A | A kind of preparation method of motor shaft wheel special environment protection lubricating oil | 雷春生 | 2017-01-04 | — | — | CN | claimed |
| CN-106267324-A | A kind of temperature response type macromolecule bio-medical adhesive and synthetic method thereof | 西北师范大学 | 2017-01-04 | — | — | CN | claimed |
| CN-104133019-B | A kind of method detecting diazabicyclo nonane enantiomter | WUHAN WUYAO TECHNOLOGY CO., LTD. (CN) | 2016-04-27 | — | — | CN | claimed |
| CN-105017286-A | Preparation method for cephalosporin anti-infective drug | SHANDONG LUOXIN PHARMACEUTICAL GROUP CO LTD | 2015-11-04 | — | — | CN | claimed |
| CN-104133019-A | Method for detecting diazabicyclo nonane enantiomorphism isomers | WUHAN WUYAO SCIENCE & TECHNOLOGY CO LTD | 2014-11-05 | — | — | CN | claimed |
| WO-2013080215-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF FLUPIRTINE AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF | ARCH PHARMALABS LIMITED (IN) | 2013-06-06 | — | — | WO | claimed |
| CN-102183589-A | Method for detecting contents of dolasetron isomer and salt thereof | CHENGDU SINO STRONG PHARMACEUTICAL CO LTD | 2011-09-14 | — | — | CN | claimed |
| EP-0538291-A1 | INTERMEDIATE USED FOR THE PREPARATION OF DEFEROXAMINE. | UPJOHN CO (US) | 1993-04-28 | — | — | EP | claimed |
| WO-1992000957-A1 | INTERMEDIATE USED FOR THE PREPARATION OF DEFEROXAMINE | THE UPJOHN COMPANY (US) | 1992-01-23 | — | — | WO | claimed |