Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL28117603 | 0.96 | ALDH1A1 (0.46) | ALDH1A1TSHRCYP2C9HPGDMAPK1 | |
| Alcohol SCHEMBL48558 | 0.96 | ALDH1A1 (0.55) | ALDH1A1TSHRCYP2C9HPGDMAPK1 | |
| Alcohol SCHEMBL11582714 | 0.92 | ALDH1A1 (0.50) | ALDH1A1TSHRCYP2C9HPGDMAPK1 | |
| Alcohol SCHEMBL18837465 | 0.92 | ALDH1A1 (0.50) | ALDH1A1TSHRCYP2C9HPGDMAPK1 | |
| Methyl Alcohol SCHEMBL946877 | 0.87 | ALDH1A1 (0.35) | ALDH1A1TSHRCYP2C9HPGDMAPK1 | |
| Water SCHEMBL11589729 | 0.87 | ALDH1A1 (0.36) | ALDH1A1CYP2C9HPGDMAPK1HSD17B10 | |
| Water SCHEMBL812316 | 0.87 | ALDH1A1 (0.36) | ALDH1A1CYP2C9HPGDMAPK1HSD17B10 | |
| Water SCHEMBL104604 | 0.87 | — | — | |
| Water SCHEMBL20920097 | 0.87 | ALDH1A1 (0.36) | ALDH1A1CYP2C9HPGDMAPK1HSD17B10 | |
| Water SCHEMBL812317 | 0.87 | ALDH1A1 (0.36) | ALDH1A1CYP2C9HPGDMAPK1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113861114-B | Morphinans and dibenzyl isoquinoline alkaloid compounds, and preparation method and application thereof | 沈阳药科大学 | 2023-06-09 | — | — | CN | claimed |
| CN-109897873-B | Enrichment method based on mixotrophic haematococcus pluvialis gamma-aminobutyric acid | 昆明理工大学 | 2022-11-18 | — | — | CN | claimed |
| CN-112552254-B | Phenanthrene compound and preparation method and application thereof | 沈阳药科大学 | 2022-08-02 | — | — | CN | claimed |
| CN-113861114-A | Morphinane and dibenzyl isoquinoline alkaloid compound and preparation method and application thereof | 沈阳药科大学 | 2021-12-31 | — | — | CN | claimed |
| CN-112142667-B | Alkaloid compound and preparation method and application thereof | 沈阳药科大学 | 2021-12-07 | — | — | CN | claimed |
| CN-110747129-B | Method for promoting grease and GABA (gamma-aminobutyric acid) in microalgae to be rapidly accumulated by GABA (gamma-aminobutyric acid) | 昆明理工大学 | 2021-08-20 | — | — | CN | claimed |
| CN-112552254-A | Phenanthrene compound and preparation method and application thereof | 沈阳药科大学 | 2021-03-26 | — | — | CN | claimed |
| CN-112142667-A | Alkaloid compound and preparation method and application thereof | 沈阳药科大学 | 2020-12-29 | — | — | CN | claimed |
| CN-110747129-A | Method for promoting grease and GABA (gamma-aminobutyric acid) in microalgae to be rapidly accumulated by GABA (gamma-aminobutyric acid) | 昆明理工大学 | 2020-02-04 | — | — | CN | claimed |
| US-20240228437-A1 | METHOD FOR PRODUCING PYRROLIDINE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2024-07-11 | — | — | US | disclosed |
| EP-4330229-A1 | METHOD FOR PRODUCING PYRROLIDINE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2024-03-06 | — | — | EP | disclosed |
| CN-117529470-A | Method for producing pyrrolidine compounds | 武田药品工业株式会社 | 2024-02-06 | — | — | CN | disclosed |
| CN-117105743-A | Purification method for recycling absolute ethyl alcohol from mixed waste solvent of ethyl alcohol, triethylamine and water | 山东新时代药业有限公司 | 2023-11-24 | — | — | CN | disclosed |
| CN-113861114-B | Morphinans and dibenzyl isoquinoline alkaloid compounds, and preparation method and application thereof | 沈阳药科大学 | 2023-06-09 | — | — | CN | disclosed |
| US-4150138-A | Method of reducing blood pressure with thiourea derivatives and guanidine derivatives | HOFFMANN-LA ROCHE INC. (US) | 1979-04-17 | — | — | US | disclosed |
| US-4127474-A | Treating a petroleum distillate with an alkanolamine hydroxide and a supported oxidation catalyst impregnated with polynuclear aromatic sulfonic acid | UOP INC. (US) | 1978-11-28 | — | — | US | disclosed |
| US-4124494-A | Treating a petroleum distillate with a supported metal phthalocyanine and an alkanolamine hydroxide | UOP INC. (US) | 1978-11-07 | — | — | US | disclosed |
| US-4113776-A | HYPOTENSIVE AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1978-09-12 | — | — | US | disclosed |
| US-4096276-A | Thiourea derivatives for treating hypertension | HOFFMANN-LA ROCHE INC. (US) | 1978-06-20 | — | — | US | disclosed |
| US-4066695-A | ANTIHYPERTENSIVE AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1978-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240228437-A1 | METHOD FOR PRODUCING PYRROLIDINE COMPOUND | PAH, SPR, IL4I1 | ALDH1A1 1008/4885TSHR 1934/4885CYP2C9 145/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.