Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.52 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.47 |
| ▸ | RAD52 | P43351 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 6/20 | 0.46 |
| ▸ | DGKA | P23743 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4852353 | 1.00 | NAAA (0.55) | NAAATSHREPHX1HCAR2RAD52 | |
| SCHEMBL4856826 | 1.00 | NAAA (0.55) | NAAATSHREPHX1HCAR2RAD52 | |
| SCHEMBL4848050 | 1.00 | NAAA (0.55) | NAAATSHREPHX1HCAR2RAD52 | |
| SCHEMBL4853689 | 0.98 | NAAA (0.52) | NAAATSHREPHX1HCAR2RAD52 | |
| SCHEMBL9839017 | 0.94 | ALDH1A1 (0.52) | NAAATSHREPHX1HCAR2RAD52 | |
| SCHEMBL1558367 | 0.92 | NAAA (0.55) | NAAATSHREPHX1HCAR2RAD52 | |
| SCHEMBL2908555 | 0.91 | ALDH1A1 (0.54) | NAAATSHREPHX1HCAR2ALDH1A1 | |
| SCHEMBL4034966 | 0.89 | NAAA (0.52) | NAAATSHREPHX1HCAR2RAD52 | |
| SCHEMBL119774 | 0.89 | NAAA (0.67) | NAAATSHREPHX1HCAR2RAD52 | |
| SCHEMBL1839798 | 0.89 | NAAA (0.67) | NAAATSHREPHX1HCAR2RAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7378548-B2 | Tertiary amine compounds having an ester structure and processes for preparing the same | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2008-05-27 | — | — | US | claimed |
| US-20060217570-A1 | Novel Tertiary Amine Compounds Having An Ester Structure And Processes For Preparing The Same | SHIN-ETSU CHEMICAL CO., LTD. | 2006-09-28 | — | — | US | claimed |
| US-7378548-B2 | Tertiary amine compounds having an ester structure and processes for preparing the same | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2008-05-27 | — | — | US | disclosed |
| EP-1253138-B1 | Novel tertiary amine compounds having an ester structure and processes for preparing same | SHINETSU CHEMICAL CO (JP) | 2007-06-27 | — | — | EP | disclosed |
| US-20060217570-A1 | Novel Tertiary Amine Compounds Having An Ester Structure And Processes For Preparing The Same | SHIN-ETSU CHEMICAL CO., LTD. | 2006-09-28 | — | — | US | disclosed |
| US-7084303-B2 | Tertiary amine compounds having an ester structure and processes for preparing same | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2006-08-01 | — | — | US | disclosed |
| US-20020193622-A1 | Novel tertiary amine compounds having an ester structure and processes for preparing same | SHIN-ETSU CHEMICAL CO., LTD. | 2002-12-19 | — | — | US | disclosed |
| EP-1253138-A2 | Novel tertiary amine compounds having an ester structure and processes for preparing same | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2002-10-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020193622-A1 | Novel tertiary amine compounds having an ester structure and processes for preparing same | PHOSPHO1, NAAA, DDAH1 | NAAA 2/4885TSHR 3525/4885EPHX1 15/4885 |
| US-20060217570-A1 | Novel Tertiary Amine Compounds Having An Ester Structure And Processes For Preparing The Same | HRH3, HRH4, HRH2 | NAAA 5/4885TSHR 2088/4885EPHX1 45/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.