Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 5/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.44 |
| ▸ | NAAA | Q02083 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 6/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4853689 | 0.93 | NAAA (0.52) | ALDH1A1TSHRHPGDATMHCAR2 | |
| SCHEMBL4855892 | 0.91 | NAAA (0.55) | ALDH1A1TSHRHCAR2NAAAEPHX1 | |
| SCHEMBL4848050 | 0.91 | NAAA (0.55) | ALDH1A1TSHRHCAR2NAAAEPHX1 | |
| SCHEMBL4856826 | 0.91 | NAAA (0.55) | ALDH1A1TSHRHCAR2NAAAEPHX1 | |
| SCHEMBL4852353 | 0.91 | NAAA (0.55) | ALDH1A1TSHRHCAR2NAAAEPHX1 | |
| SCHEMBL2906107 | 0.91 | ALDH1A1 (0.43) | ALDH1A1TSHRHPGDATMHCAR2 | |
| SCHEMBL2904163 | 0.91 | ALDH1A1 (0.54) | ALDH1A1TSHRHPGDATMHCAR2 | |
| SCHEMBL9839017 | 0.89 | ALDH1A1 (0.52) | ALDH1A1TSHRHPGDATMHCAR2 | |
| SCHEMBL37837 | 0.88 | ALDH1A1 (0.67) | ALDH1A1TSHRHPGDATMHCAR2 | |
| SCHEMBL696985 | 0.86 | ALDH1A1 (0.54) | ALDH1A1TSHRHPGDATMHCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7378548-B2 | Tertiary amine compounds having an ester structure and processes for preparing the same | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2008-05-27 | — | — | US | claimed |
| US-20060217570-A1 | Novel Tertiary Amine Compounds Having An Ester Structure And Processes For Preparing The Same | SHIN-ETSU CHEMICAL CO., LTD. | 2006-09-28 | — | — | US | claimed |
| EP-2217564-A1 | COMPLEX PANTOIC ACID ESTER NEOPENTYL SULFONYL ESTER CYCLIZATION RELEASE PRODRUGS OF ACAMPROSATE, COMPOSITIONS THEREOF, AND METHODS OF USE | XenoPort, Inc. (US) | 2010-08-18 | — | — | EP | disclosed |
| WO-2010035032-A1 | CALCIUM ION CHANNEL MODULATORS & USES THEREOF | LECTUS THERAPEUTICS LIMITED (GB) | 2010-04-01 | — | — | WO | disclosed |
| WO-2009133387-A1 | INDOLE- 3 -GLYOXYLAMIDE DERIVATIVES FOR USE AS CALCIUM ION CHANNEL MODULATORS | LECTUS THERAPEUTICS LIMITED (GB) | 2009-11-05 | — | — | WO | disclosed |
| US-20090076147-A1 | COMPLEX PANTOIC ACID ESTER NEOPENTYL SULFONYL ESTER CYCLIZATION RELEASE PRODRUGS OF ACAMPROSATE, COMPOSITIONS THEREOF, AND METHODS OF USE | XENOPORT, INC. | 2009-03-19 | — | — | US | disclosed |
| WO-2009033054-A1 | COMPLEX PANTOIC ACID ESTER NEOPENTYL SULFONYL ESTER CYCLIZATION RELEASE PRODRUGS OF ACAMPROSATE, COMPOSITIONS THEREOF, AND METHODS OF USE | XENOPORT, INC. (US) | 2009-03-12 | — | — | WO | disclosed |
| US-7378548-B2 | Tertiary amine compounds having an ester structure and processes for preparing the same | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2008-05-27 | — | — | US | disclosed |
| EP-1919290-A2 | METHODS AND PRODUCTS FOR TREATMENT OF DISEASES | DMI Biosciences, Inc. (US) | 2008-05-14 | — | — | EP | disclosed |
| EP-1898951-A1 | PHARMACEUTICAL PREPARATION CONTAINING AN ANGIOTENSIN II RECEPTOR ANTAGONIST AND A CALCIUM CHANNEL BLOCKER | Daiichi Sankyo Company, Limited (JP) | 2008-03-19 | — | — | EP | disclosed |
| EP-1253138-B1 | Novel tertiary amine compounds having an ester structure and processes for preparing same | SHINETSU CHEMICAL CO (JP) | 2007-06-27 | — | — | EP | disclosed |
| US-5073551-A | Antibiotics | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1991-12-17 | — | — | US | disclosed |
| US-5071443-A | BLUE AZO DYESTUFF MIXTURE FOR STRONG BLUE COLOR ON HYDROPHOBIC FIBERS | CASSELLA AKTIENGESELLSCHAFT (DE) | 1991-12-10 | — | — | US | disclosed |
| EP-0391121-A1 | Monoazo dyes, their preparation and use | CASSELLA Aktiengesellschaft (DE) | 1990-10-10 | — | — | EP | disclosed |
| EP-0335390-A2 | Novel cephalosporin compounds | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1989-10-04 | — | — | EP | disclosed |
| US-4808620-A | ANTIINFLAMMATORY, ANALGESICS, ANTIPYRETIC, ANTIALLERGENS, ANTIARTHRITIC, ANTIRHEUMATIC AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1989-02-28 | — | — | US | disclosed |
| EP-0254241-A1 | Pyrazolopyridine compounds, their preparation and use | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1988-01-27 | — | — | EP | disclosed |
| US-4678476-A | HIGH TINCTORIAL STRENGTH, COLORFASTNESS | CASSELLA AKTIENGESELLSCHAFT (DE) | 1987-07-07 | — | — | US | disclosed |
| EP-0222255-A2 | Mixtures of blue disperse dyes and their use in dyeing polyesters | CASSELLA Aktiengesellschaft (DE) | 1987-05-20 | — | — | EP | disclosed |
| US-4496562-A | 7-Substituted-3-cephem-4-carboxylic acid esters | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1985-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090076147-A1 | COMPLEX PANTOIC ACID ESTER NEOPENTYL SULFONYL ESTER CYCLIZATION RELEASE PRODRUGS OF ACAMPROSATE, COMPOSITIONS THEREOF, AND METHODS OF USE | ADSL, SLC19A1, SLC25A21 | ALDH1A1 1514/4885TSHR 2112/4885HPGD 380/4885 |
| US-20060217570-A1 | Novel Tertiary Amine Compounds Having An Ester Structure And Processes For Preparing The Same | HRH3, HRH4, HRH2 | ALDH1A1 551/4885TSHR 2088/4885HPGD 1854/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.