Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 5/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ESRRG | P62508 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4858208 | 0.79 | GAA (0.43) | LMNARAB9AALDH1A1HTTTDP1 | |
| SCHEMBL15428444 | 0.74 | HCAR2 (0.50) | LMNARAB9ANR1H4EPHX2ALDH1A1 | |
| SCHEMBL15428443 | 0.74 | HCAR2 (0.50) | LMNARAB9ANR1H4EPHX2ALDH1A1 | |
| SCHEMBL3278159 | 0.73 | LMNA (0.68) | LMNARAB9ANR1H4EPHX2ALDH1A1 | |
| SCHEMBL17213800 | 0.73 | ADH1B (0.47) | RAB9AALDH1A1TDP1MAPTKMT2A | |
| SCHEMBL4742628 | 0.72 | TP53 (0.42) | LMNANR1H4EPHX2ALDH1A1MAPT | |
| SCHEMBL627479 | 0.71 | ADH1B (0.54) | RAB9AALDH1A1TDP1MAPTKMT2A | |
| SCHEMBL6567605 | 0.71 | ALDH1A1 (0.47) | LMNARAB9ANR1H4EPHX2ALDH1A1 | |
| SCHEMBL6567600 | 0.71 | ALDH1A1 (0.47) | LMNARAB9ANR1H4EPHX2ALDH1A1 | |
| SCHEMBL22307312 | 0.71 | EPHX2 (0.47) | LMNARAB9ANR1H4EPHX2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008096075-A2 | METHOD FOR THE ASYMMETRIC HYDROGENATION OF ENAMINE AND DEVICE FOR REALISING SAID METHOD | HOLIS TECHNOLOGIES (FR) | 2008-08-14 | — | — | WO | disclosed |