Sugi Predict

Sugi Predict / Compounds / SCHEMBL485867

SCHEMBL485867

SCHEMBL485867

CCCCCCCC(Cl)(Cl)CC(=O)OCC

nearest known ligand 0.45

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 1/20 0.45
▸ MAPT P10636 1/20 0.45
▸ KMT2A Q03164 1/20 0.45
▸ ATM Q13315 1/20 0.45
▸ L3MBTL1 Q9Y468 1/20 0.45
▸ NAAA Q02083 1/20 0.40
▸ DGKA P23743 1/20 0.40
▸ GAA P10253 2/20 0.40
▸ MGAM O43451 1/20 0.39
▸ SI P14410 1/20 0.39
▸ MGAM2 Q2M2H8 1/20 0.39
▸ CYP4F2 P78329 1/20 0.39
▸ CYP4A11 Q02928 1/20 0.39
▸ SMPD1 P17405 2/20 0.38
▸ CES2 O00748 1/20 0.38
▸ FDPS P14324 1/20 0.38
▸ LPAR1 Q92633 1/20 0.38
▸ LPAR3 Q9UBY5 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL548470 1.00 MEN1 (0.45) MEN1MAPTKMT2AATML3MBTL1
SCHEMBL4341048 0.98 MEN1 (0.42) MEN1MAPTKMT2AATML3MBTL1
Heptane SCHEMBL6925620 0.86 NAAA (0.40) MEN1MAPTKMT2AATML3MBTL1
SCHEMBL9309086 0.83 MEN1 (0.43) MEN1MAPTKMT2AATML3MBTL1
Hexane SCHEMBL9472263 0.81 GAA (0.44) MEN1MAPTKMT2AATML3MBTL1
SCHEMBL19861329 0.80 FFAR1 (0.48) MEN1MAPTKMT2AATML3MBTL1
SCHEMBL20457453 0.80 FFAR1 (0.48) MEN1MAPTKMT2AATML3MBTL1
SCHEMBL5864262 0.79 GAA (0.43) GAAMGAMSIMGAM2CYP4F2
SCHEMBL11209470 0.79 MEN1 (0.45) MEN1MAPTKMT2AATML3MBTL1
SCHEMBL19861159 0.79 MEN1 (0.49) MEN1MAPTKMT2AATML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12012411-B2 Viral replication inhibitors KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2024-06-18 — — US disclosed
CN-116332999-A Organic electroluminescent material and device 环球展览公司 2023-06-27 — — CN disclosed
CN-108440370-B Inhibitors of viral replication 鲁汶天主教大学 2021-07-30 — — CN disclosed
EP-3617192-A1 VIRAL REPLICATION INHIBITORS Katholieke Universiteit Leuven K.U. Leuven R&D (BE) 2020-03-04 — — EP disclosed
US-10550123-B2 Viral replication inhibitors KATHOLIEKE UNIVERSITEIT LEUVEN, K.U. LEUVEN R&D (BE) 2020-02-04 — — US disclosed
US-20190337954-A1 VIRAL REPLICATION INHIBITORS KATHOLIEKE UNIVERSITEIT LEUVEN, K.U. LEUVEN R&D (BE) 2019-11-07 — — US disclosed
EP-2760831-B1 VIRAL REPLICATION INHIBITORS UNIV LEUVEN KATH (BE) 2019-08-07 — — EP disclosed
CN-104024223-A Inhibitors of viral replication UNIV LEUVEN KATH 2014-09-03 — — CN disclosed
EP-2760831-A1 VIRAL REPLICATION INHIBITORS Katholieke Universiteit Leuven (BE) 2014-08-06 — — EP disclosed
US-20140213586-A1 VIRAL REPLICATION INHIBITORS KATHOLIEKE UNIVERSITEIT LEUVEN, K.U. LEUVEN R&D (BE) 2014-07-31 — — US disclosed
EP-0577191-B1 Photographic element and process comprising a bleach accelerator releasing compound and methods of making such compound EASTMAN KODAK CO (US) 1997-05-21 — — EP disclosed
EP-0751425-A1 Photographic element containing a coupler capable of releasing a photographically useful group EASTMAN KODAK COMPANY (US) 1997-01-02 — — EP disclosed
US-5358828-A Coupler capable of forming wash-out dye EASTMAN KODAK COMPANY (US) 1994-10-25 — — US disclosed
US-5318879-A Photographic element comprising a bleach accelerator releasing compound EASTMAN KODAK COMPANY (US) 1994-06-07 — — US disclosed
US-5300406-A Coupler which forms dye that washes out during processing EASTMAN KODAK COMPANY (US) 1994-04-05 — — US disclosed
US-5286859-A Bleach accelerating releasing coupler; forming chloroformate with phosgene, reacting with a thiol EASTMAN KODAK COMPANY (US) 1994-02-15 — — US disclosed
EP-0577190-A2 Photographic element comprising a bleach accelerator releasing compound containing an acid solubilizing group EASTMAN KODAK COMPANY (US) 1994-01-05 — — EP disclosed
EP-0577193-A1 Photographic element comprising a combination of a development inhibiting releasing coupler and a bleach accelerator releasing compound EASTMAN KODAK COMPANY (US) 1994-01-05 — — EP disclosed
EP-0577191-A2 Photographic element and process comprising a bleach accelerator releasing compound and methods of making such compound EASTMAN KODAK COMPANY (US) 1994-01-05 — — EP disclosed
EP-0577192-A1 Photographic element comprising a dir coupler and a barc coupler containing an acid solubilizing group EASTMAN KODAK COMPANY (US) 1994-01-05 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140213586-A1 VIRAL REPLICATION INHIBITORS EIF2AK2, MAVS, ZC3HAV1 MEN1 3390/4885MAPT 3097/4885KMT2A 2425/4885
US-20190337954-A1 VIRAL REPLICATION INHIBITORS EIF2AK2, MAVS, ZC3HAV1 MEN1 3390/4885MAPT 3097/4885KMT2A 2425/4885
US-10550123-B2 Viral replication inhibitors EIF2AK2, MAVS, ZC3HAV1 MEN1 3390/4885MAPT 3097/4885KMT2A 2425/4885
US-12012411-B2 Viral replication inhibitors EIF2AK2, MAVS, ZC3HAV1 MEN1 3390/4885MAPT 3097/4885KMT2A 2425/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.