SCHEMBL548470

SCHEMBL548470

CCCCCCC(Cl)(Cl)CC(=O)OCC

nearest known ligand 0.45

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.45
MAPT P10636 1/20 0.45
KMT2A Q03164 1/20 0.45
ATM Q13315 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
NAAA Q02083 1/20 0.40
DGKA P23743 1/20 0.40
GAA P10253 2/20 0.40
MGAM O43451 1/20 0.39
SI P14410 1/20 0.39
MGAM2 Q2M2H8 1/20 0.39
CYP4F2 P78329 1/20 0.39
CYP4A11 Q02928 1/20 0.39
SMPD1 P17405 2/20 0.38
CES2 O00748 1/20 0.38
FDPS P14324 1/20 0.38
LPAR1 Q92633 1/20 0.38
LPAR3 Q9UBY5 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL485867 1.00 MEN1 (0.45) MEN1MAPTKMT2AATML3MBTL1
SCHEMBL4341048 0.98 MEN1 (0.42) MEN1MAPTKMT2AATML3MBTL1
Heptane SCHEMBL6925620 0.86 NAAA (0.40) MEN1MAPTKMT2AATML3MBTL1
SCHEMBL9309086 0.83 MEN1 (0.43) MEN1MAPTKMT2AATML3MBTL1
Hexane SCHEMBL9472263 0.81 GAA (0.44) MEN1MAPTKMT2AATML3MBTL1
SCHEMBL19861329 0.80 FFAR1 (0.48) MEN1MAPTKMT2AATML3MBTL1
SCHEMBL20457453 0.80 FFAR1 (0.48) MEN1MAPTKMT2AATML3MBTL1
SCHEMBL5864262 0.79 GAA (0.43) GAAMGAMSIMGAM2CYP4F2
SCHEMBL11209470 0.79 MEN1 (0.45) MEN1MAPTKMT2AATML3MBTL1
SCHEMBL19861159 0.79 MEN1 (0.49) MEN1MAPTKMT2AATML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 293 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024014885-A1 NOVEL BICYCLIC HETEROARYL COMPOUND AND USE THEREOF 일동제약(주) 2024-01-18 WO disclosed
US-20240016049-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-01-11 US disclosed
US-11832509-B2 Organometallic compound, organic light-emitting device including the same, and diagnostic composition including the organometallic compound SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-11-28 US disclosed
EP-4212539-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2023-07-19 EP disclosed
CN-116332999-A Organic electroluminescent material and device 环球展览公司 2023-06-27 CN disclosed
US-20220213131-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-07-07 US disclosed
CN-114539323-A Organic electroluminescent material and device 环球展览公司 2022-05-27 CN disclosed
US-20210214385-A1 INHIBITORS OF D-AMINO ACID OXIDASE AND USES THEREOF SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) 2021-07-15 US disclosed
CN-107614510-B Iridium complex compound, organic electroluminescent element containing iridium complex compound, display device, and lighting device 三菱化学株式会社 2021-04-20 CN disclosed
EP-3802478-A1 POTENT INHIBITORS OF D-AMINO ACID OXIDASE (DAAO) AND USES THEREOF Syneurx International (Taiwan) Corp. (TW) 2021-04-14 EP disclosed
US-5037986-A Olefinic 1H-imidazo[4,5-c]quinolin-4-amines MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-08-06 US disclosed
EP-0255098-B1 Novel 8-(lower alkyl) bicyclo [4.2.0] octane derivatives with valuable therapeutic properties SYNTEX (U.S.A.) INC. (US) 1991-05-29 EP disclosed
CN-1046163-A The heterocycleamide prostanoid analogue that is used for the treatment of the interior phenylene 7-oxabicyclo heptyl replacement of thrombosis and vasospasm disease SQUIBB & SONS INC (US) 1990-10-17 CN disclosed
EP-0389302-A1 Olefinic 1H-imidazo [4,5-c]quinolin-4-amines RIKER LABORATORIES, INC. (US) 1990-09-26 EP disclosed
US-4929624-A Olefinic 1H-imidazo(4,5-c)quinolin-4-amines MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1990-05-29 US disclosed
EP-0196617-B1 [4.2.0]bicyclooctane derivatives, process for their preparation and pharmaceutical compositions containing same SYNTEX (U.S.A.) INC. (US) 1989-05-31 EP disclosed
EP-0255098-A1 Novel 8-(lower alkyl) bicyclo [4.2.0] octane derivatives with valuable therapeutic properties SYNTEX (U.S.A.) INC. (US) 1988-02-03 EP disclosed
US-4678805-A Novel 8-(lower alkyl)bicyclo[4.2.0]octane derivatives with valuable therapeutic properties SYNTEX (U.S.A.) INC. (US) 1987-07-07 US disclosed
EP-0196617-A1 [4.2.0]bicyclooctane derivatives, process for their preparation and pharmaceutical compositions containing same SYNTEX (U.S.A.) INC. (US) 1986-10-08 EP disclosed
US-4608388-A Novel [4,2,0]bicyclooctane derivatives with valuable therapeutic properties SYNTEX (U.S.A.) INC. (US) 1986-08-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240016049-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OPRD1, OXER1 MEN1 3593/4885MAPT 3979/4885KMT2A 3521/4885
US-20210214385-A1 INHIBITORS OF D-AMINO ACID OXIDASE AND USES THEREOF DAO, DDO, DDC MEN1 4706/4885MAPT 2765/4885KMT2A 1692/4885
US-20220213131-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, LOXL1, OCIAD2 MEN1 2627/4885MAPT 2885/4885KMT2A 4084/4885
US-11832509-B2 Organometallic compound, organic light-emitting device including the same, and diagnostic composition including the organometallic compound L1CAM, NOM1, MEN1 MEN1 3/4885MAPT 852/4885KMT2A 2035/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.