Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 17/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 15/20 | 0.41 |
| ▸ | CASP1 | P29466 | 15/20 | 0.41 |
| ▸ | CASP7 | P55210 | 15/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 14/20 | 0.41 |
| ▸ | USP2 | O75604 | 12/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 10/20 | 0.41 |
| ▸ | TSHR | P16473 | 7/20 | 0.41 |
| ▸ | MEN1 | O00255 | 7/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.41 |
| ▸ | GLA | P06280 | 3/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 8/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | MAPK7 | Q13164 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14158808 | 0.85 | CDK4 (0.37) | — | |
| SCHEMBL4855863 | 0.83 | RXFP1 (0.36) | ALDH1A1MEN1KMT2AMAPK1LMNA | |
| SCHEMBL4852983 | 0.82 | PTGS2 (0.36) | USP2MEN1KMT2ALMNA | |
| SCHEMBL14158877 | 0.81 | MAPK14 (0.33) | TSHRMEN1KMT2AMAPK1 | |
| SCHEMBL4854308 | 0.80 | MAPK14 (0.37) | — | |
| SCHEMBL14163794 | 0.79 | HSP90AA1 (0.33) | — | |
| SCHEMBL14158876 | 0.79 | HSP90AA1 (0.35) | LMNA | |
| SCHEMBL4848710 | 0.78 | CYP1A2 (0.45) | ALDH1A1CYP1A2CASP1CASP7HSD17B10 | |
| SCHEMBL4848607 | 0.77 | MAPK14 (0.39) | — | |
| SCHEMBL4848602 | 0.77 | MAPK14 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080139588-A1 | Pyrrolo[2,3-d]pyrimidine cytokine inhibitors | THE PROCTER & GAMBLE COMPANY | 2008-06-12 | — | — | US | disclosed |
| US-7319102-B1 | Pyrrolo[2,3-d]pyrimidine cytokine inhibitors | THE PROCTER & GAMBLE COMPANY (US) | 2008-01-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080139588-A1 | Pyrrolo[2,3-d]pyrimidine cytokine inhibitors | DPYD, IL1B, IL6 | ALDH1A1 566/4885CYP1A2 2019/4885CASP1 447/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.