Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 18/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 14/20 | 0.45 |
| ▸ | USP2 | O75604 | 12/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 12/20 | 0.45 |
| ▸ | TSHR | P16473 | 11/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 11/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 9/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | CASP1 | P29466 | 5/20 | 0.41 |
| ▸ | CASP7 | P55210 | 5/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4857351 | 0.84 | CYP1A2 (0.39) | CYP1A2ALDH1A1USP2CYP2C9TSHR | |
| SCHEMBL4856363 | 0.79 | CYP1A2 (0.48) | CYP1A2ALDH1A1USP2CYP2C9TSHR | |
| SCHEMBL14163794 | 0.79 | HSP90AA1 (0.33) | — | |
| SCHEMBL4858892 | 0.78 | ALDH1A1 (0.41) | CYP1A2ALDH1A1USP2CYP2C9TSHR | |
| SCHEMBL4855863 | 0.78 | RXFP1 (0.36) | ALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL14158877 | 0.78 | MAPK14 (0.33) | TSHRMEN1KMT2AMAPK1CHRNA7 | |
| SCHEMBL4854308 | 0.78 | MAPK14 (0.37) | — | |
| SCHEMBL4852983 | 0.78 | PTGS2 (0.36) | USP2MEN1KMT2A | |
| SCHEMBL14158876 | 0.77 | HSP90AA1 (0.35) | — | |
| SCHEMBL14158808 | 0.76 | CDK4 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080139588-A1 | Pyrrolo[2,3-d]pyrimidine cytokine inhibitors | THE PROCTER & GAMBLE COMPANY | 2008-06-12 | — | — | US | claimed |
| US-20080139588-A1 | Pyrrolo[2,3-d]pyrimidine cytokine inhibitors | THE PROCTER & GAMBLE COMPANY | 2008-06-12 | — | — | US | disclosed |
| US-7319102-B1 | Pyrrolo[2,3-d]pyrimidine cytokine inhibitors | THE PROCTER & GAMBLE COMPANY (US) | 2008-01-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080139588-A1 | Pyrrolo[2,3-d]pyrimidine cytokine inhibitors | DPYD, IL1B, IL6 | CYP1A2 2019/4885ALDH1A1 566/4885USP2 1948/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.