SCHEMBL4858902

SCHEMBL4858902

O=C(O)c1ccc(Oc2ccccc2C(F)(F)F)c(C(F)(F)F)c1C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXRA P19793 1/20 0.43
RXRB P28702 1/20 0.43
RXRG P48443 1/20 0.43
IDO1 P14902 1/20 0.41
MRGPRX4 Q96LA9 1/20 0.40
TAS2R14 Q9NYV8 2/20 0.40
LPAR1 Q92633 1/20 0.40
LPAR5 Q9H1C0 1/20 0.40
STK39 Q9UEW8 1/20 0.40
PPARG P37231 1/20 0.40
RBP4 P02753 2/20 0.40
FABP4 P15090 1/20 0.39
RORC P51449 1/20 0.38
HTT P42858 1/20 0.38
THRA P10827 1/20 0.38
THRB P10828 1/20 0.38
GRIK1 P39086 1/20 0.37
AKR1C3 P42330 1/20 0.37
AKR1C2 P52895 1/20 0.37
MEN1 O00255 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3193336 0.91 HTT (0.45) IDO1TAS2R14HTTALDH1A1KMT2A
SCHEMBL10626633 0.90 ALDH1A1 (0.40) RXRARXRBRXRGIDO1MRGPRX4
SCHEMBL3188656 0.88 TAS2R14 (0.38) RXRARXRBRXRGIDO1MRGPRX4
SCHEMBL3755844 0.87 HTT (0.39) IDO1TAS2R14FABP4HTTAKR1C3
SCHEMBL29088055 0.84 MRGPRX4 (0.46) RXRARXRBRXRGIDO1MRGPRX4
SCHEMBL7189938 0.84 TTR (0.42) STK39ALDH1A1
SCHEMBL4854755 0.84 FABP3 (0.38) RXRARXRBRXRGFABP4HTT
SCHEMBL29962914 0.84 RHEB (0.39) LPAR1LPAR5STK39THRATHRB
SCHEMBL10626641 0.83 HNF4A (0.40) RXRARXRBRXRGIDO1FABP4
SCHEMBL3788013 0.83 TAS2R14 (0.38) RXRARXRBRXRGMRGPRX4TAS2R14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117202984-A Polyimide porous film 东京应化工业株式会社 2023-12-08 CN disclosed
US-20130161864-A1 SUBSTRATE STRUCTURE AND METHOD FOR MAKING THE SAME CHI MEI CORPORATION (TW) 2013-06-27 US disclosed
US-7450803-B2 Optical waveguide HITACHI CHEMICAL COMPANY, LTD. (JP) 2008-11-11 US disclosed
US-20070086705-A1 Optical waveguide HITACHI CHEMICAL COMPANY, LTD. (JP) 2007-04-19 US disclosed
US-20030054184-A1 Optical element, method for the production thereof and optical module HITACHI CHEMICAL CO., LTD. (JP) 2003-03-20 US disclosed
US-5598501-A Polyimide optical waveguide and method of manufacturing the same NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1997-01-28 US disclosed