SCHEMBL3788013

SCHEMBL3788013

O=C(O)c1ccc(Oc2c(-c3cccc(C(F)(F)F)c3Oc3ccc(C(=O)O)c(C(=O)O)c3C(F)(F)F)cccc2C(F)(F)F)c(C(F)(F)F)c1C(=O)O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAS2R14 Q9NYV8 2/20 0.38
FABP4 P15090 1/20 0.37
ALDH1A1 P00352 3/20 0.35
HPGD P15428 2/20 0.35
CMA1 P23946 1/20 0.34
MRGPRX4 Q96LA9 3/20 0.33
GRIK1 P39086 1/20 0.33
AKR1C3 P42330 1/20 0.33
AKR1C2 P52895 1/20 0.33
KMO O15229 2/20 0.33
RXRA P19793 1/20 0.33
RXRB P28702 1/20 0.33
RXRG P48443 1/20 0.33
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
KDM4E B2RXH2 1/20 0.32
USP2 O75604 1/20 0.32
CYP2C19 P33261 1/20 0.32
HSD17B10 Q99714 1/20 0.32
PARP1 P09874 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4858140 0.96 ALDH1A1 (0.39) TAS2R14FABP4ALDH1A1HPGDMRGPRX4
SCHEMBL3188656 0.90 TAS2R14 (0.38) TAS2R14FABP4CMA1MRGPRX4GRIK1
SCHEMBL3744942 0.85 TAS2R14 (0.40) TAS2R14FABP4ALDH1A1HPGDMRGPRX4
SCHEMBL10626633 0.84 ALDH1A1 (0.40) TAS2R14FABP4ALDH1A1HPGDMRGPRX4
SCHEMBL4858902 0.83 RXRA (0.43) TAS2R14FABP4ALDH1A1MRGPRX4GRIK1
SCHEMBL10628408 0.82 KDM4E (0.33) TAS2R14FABP4ALDH1A1HPGDCMA1
SCHEMBL3178432 0.81 HNF4A (0.38) FABP4RXRARXRBRXRG
SCHEMBL3755844 0.81 HTT (0.39) TAS2R14FABP4ALDH1A1HPGDAKR1C3
SCHEMBL10626641 0.80 HNF4A (0.40) FABP4ALDH1A1RXRARXRBRXRG
SCHEMBL3193336 0.79 HTT (0.45) TAS2R14ALDH1A1HPGDKMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0400635-B1 Liquid crystal device CANON KK (JP) 1995-09-27 EP claimed
US-5192596-A Polyimide CANON KABUSHIKI KAISHA (JP) 1993-03-09 US claimed
WO-2023189319-A1 AMINO COMPOUND, POLYAMIDE ACID AND POLYIMIDE USING SAID AMINO COMPOUND, AND METHOD FOR PRODUCING SAME 日鉄ケミカル&マテリアル株式会社 2023-10-05 WO disclosed
WO-2023106369-A1 POLYIMIDE FOR SPACECRAFT, POLYIMIDE FILM FOR SPACECRAFT, AND SPACECRAFT MEMBER INCLUDING SAME 日鉄ケミカル&マテリアル株式会社 2023-06-15 WO disclosed
US-20210340325-A1 POLYIMIDE PRECURSOR, POLYIMIDE PRODUCED FROM SAME, AND FLEXIBLE DEVICE NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2021-11-04 US disclosed
US-9688815-B2 Method for producing polyimide precursor and method for producing polyimide RICOH COMPANY, LTD. (JP) 2017-06-27 US disclosed
US-20160122474-A1 METHOD FOR PRODUCING POLYIMIDE PRECURSOR AND METHOD FOR PRODUCING POLYIMIDE RICHO COMPANY, LTD. (JP) 2016-05-05 US disclosed
EP-3004211-A1 METHOD FOR PRODUCING POLYIMIDE PRECURSOR AND METHOD FOR PRODUCING POLYIMIDE Ricoh Company, Ltd. (JP) 2016-04-13 EP disclosed
WO-2014192665-A1 METHOD FOR PRODUCING POLYIMIDE PRECURSOR AND METHOD FOR PRODUCING POLYIMIDE RICOH COMPANY, LTD. (JP) 2014-12-04 WO disclosed
US-20120177425-A1 GLOSSY SURFACE FORMING APPARATUS AND GLOSSY SURFACE FORMING METHOD KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2012-07-12 US disclosed
US-20100329616-A1 PHOTOSENSITIVE RESIN COMPOSITION, METHOD FOR CONTROL OF REFRACTIVE INDEX, AND OPTICAL WAVEGUIDE AND OPTICAL COMPONENT USING THE SAME NEC CORPORATION (JP) 2010-12-30 US disclosed
EP-0720030-A1 Waveguide device and method for production thereof HOECHST AKTIENGESELLSCHAFT (DE) 1996-07-03 EP disclosed
EP-0400635-B1 Liquid crystal device CANON KK (JP) 1995-09-27 EP disclosed
US-5426525-A Ferroelectric smectic liquid crystal device CANON KABUSHIKI KAISHA (JP) 1995-06-20 US disclosed
EP-0616234-A2 Polyimide optical waveguide and method of manufacturing the same NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1994-09-21 EP disclosed
US-5316805-A Liquid crystal device CANON KABUSHIKI KAISHA (JP) 1994-05-31 US disclosed
EP-0219336-B1 LIQUID CRYSTAL ORIENTATION CONTROLLING FILM AND LIQUID CRYSTAL DEVICE USING THE SAME Hitachi Chemical Co., Ltd. (JP) 1993-07-21 EP disclosed
US-5192596-A Polyimide CANON KABUSHIKI KAISHA (JP) 1993-03-09 US disclosed
US-5108201-A From 3,3'-diamino-2,2'-bis(trifluoromethyl)biphenyl monomer NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1992-04-28 US disclosed
EP-0219336-A2 Liquid crystal orientation controlling film and liquid crystal device using the same Hitachi Chemical Co., Ltd. (JP) 1987-04-22 EP disclosed