Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 13/20 | 0.72 |
| ▸ | APP | P05067 | 13/20 | 0.70 |
| ▸ | BCHE | P06276 | 9/20 | 0.69 |
| ▸ | MEN1 | O00255 | 1/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4859221 | 0.91 | ACHE (0.74) | ACHEAPPBCHEMEN1KMT2A | |
| SCHEMBL4863132 | 0.90 | ACHE (0.73) | ACHEAPPBCHEMEN1KMT2A | |
| SCHEMBL4863020 | 0.85 | APP (0.71) | ACHEAPPMEN1KMT2A | |
| SCHEMBL4859121 | 0.85 | APP (0.68) | ACHEAPPBCHEKMT2A | |
| SCHEMBL4864375 | 0.84 | APP (0.60) | ACHEAPPBCHEMEN1KMT2A | |
| SCHEMBL4861484 | 0.84 | CYP1A2 (0.64) | ACHEMEN1KMT2A | |
| SCHEMBL5270283 | 0.84 | CYP1A2 (0.55) | ACHEAPPMEN1KMT2A | |
| SCHEMBL4868159 | 0.83 | APP (0.51) | ACHEAPPBCHEMEN1KMT2A | |
| SCHEMBL3121034 | 0.82 | APP (0.79) | ACHEAPPBCHEMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL3123789 | 0.81 | APP (0.77) | ACHEAPPBCHEMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2008526734-A | — | — | 2008-07-24 | — | — | JP | claimed |
| EP-1844023-A1 | QUINAZOLINE DERIVATIVES FOR THE TREATMENT AND PREVENTION OF DIABETES AND OBESITY | SK CHEMICALS CO., LTD. (KR) | 2007-10-17 | — | — | EP | claimed |
| WO-2006071095-A1 | QUINAZOLINE DERIVATIVES FOR THE TREATMENT AND PREVENTION OF DIABETES AND OBESITY | SK CHEMICALS CO., LTD. (KR) | 2006-07-06 | — | — | WO | claimed |
| EP-1844023-A1 | QUINAZOLINE DERIVATIVES FOR THE TREATMENT AND PREVENTION OF DIABETES AND OBESITY | SK CHEMICALS CO., LTD. (KR) | 2007-10-17 | — | — | EP | disclosed |
| WO-2006071095-A1 | QUINAZOLINE DERIVATIVES FOR THE TREATMENT AND PREVENTION OF DIABETES AND OBESITY | SK CHEMICALS CO., LTD. (KR) | 2006-07-06 | — | — | WO | disclosed |