SCHEMBL4864375

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4863020	0.92	APP (0.71)	APPKMT2AMEN1LMNACYP1A2
	SCHEMBL4864609	0.91	APP (0.57)	APPKMT2AMEN1LMNACYP1A2
	SCHEMBL4859121	0.89	APP (0.68)	APPKMT2ALMNACYP1A2CYP3A4
	SCHEMBL4866192	0.89	APP (0.61)	APPKMT2AMEN1LMNACYP1A2
	SCHEMBL4868159	0.87	APP (0.51)	APPKMT2AMEN1LMNACYP1A2
	SCHEMBL4868169	0.84	APP (0.70)	APPKMT2AMEN1LMNACYP1A2
	SCHEMBL4859418	0.84	ACHE (0.72)	APPKMT2AMEN1ACHEBCHE
	SCHEMBL5273800	0.83	CYP1A2 (0.66)	APPKMT2AMEN1LMNACYP1A2
	SCHEMBL5270283	0.83	CYP1A2 (0.55)	APPKMT2AMEN1LMNACYP1A2
	SCHEMBL4861484	0.81	CYP1A2 (0.64)	KMT2AMEN1LMNACYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.