SCHEMBL4859448

SCHEMBL4859448

CCCCCCCCCCCCC(CCCC(COc1ccccc1O)c1ccccc1)c1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
JAK2 O60674 1/20 0.38
LMNA P02545 1/20 0.38
GAA P10253 1/20 0.38
MAPT P10636 1/20 0.38
HTR1A P08908 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
PPARG P37231 2/20 0.36
PRSS1 P07477 1/20 0.36
PRSS2 P07478 1/20 0.36
PRSS3 P35030 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL987751 0.82 NR5A1 (0.51) LMNAMAPTHTR1AMEN1KMT2A
SCHEMBL9437435 0.80 PRSS1 (0.47) JAK2LMNAGAAMAPTHTR1A
SCHEMBL18038533 0.79 HTR1A (0.49) JAK2LMNAGAAMAPTHTR1A
SCHEMBL9488200 0.78 LMNA (0.42) JAK2LMNAGAAMAPTHTR1A
SCHEMBL23849703 0.78 NR1I2 (0.49)
SCHEMBL21633771 0.78 NR1I2 (0.49)
SCHEMBL20291563 0.78 NR1I2 (0.49)
SCHEMBL21633686 0.78 NR1I2 (0.49)
SCHEMBL21633712 0.78 NR1I2 (0.49)
SCHEMBL7534046 0.78 NR1I2 (0.49)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4490508-A1 OXIDATIVE STABILITY TEST METHODS FOR CHEMICALLY RECYCLED PLASTIC FEEDSTOCKS ECOLAB USA INC. (US) 2025-01-15 EP disclosed
WO-2023172410-A1 OXIDATIVE STABILITY TEST METHODS FOR CHEMICALLY RECYCLED PLASTIC FEEDSTOCKS ECOLAB USA INC. (US) 2023-09-14 WO disclosed
US-7358365-B2 Process for the controlled increase in the molecular weight of polyethylenes CIBA SPECIALTY CHEMICALS CORPORATION (US) 2008-04-15 US disclosed
US-20060128903-A1 Process for the controlled increase in the molecular weight of polyethylenes ROTH MICHAEL 2006-06-15 US disclosed
US-6767949-B1 REDUCING AGENT COMPRISING PHOSPHORUS COMPOUND, SULFUR COMPOUND OR ETHYLENICALLY UNSATURATED CYCLIC COMPOUND; DISCOLORATION INHIBITION CIBA SPECIALTY CHEMICALS CORPORATION 2004-07-27 US disclosed
US-20040013619-A1 Heteroaryl substituted hydroxyphenyltriazine uv-absorbers CIBA SPECIALTY CHEMICALS CORP. 2004-01-22 US disclosed
US-20030191239-A1 Stabilizer agents comprising heterocyclic amines such as Tinuvin\" or Cyasorb\", used stabilization of addition polymers from degradation induced by light, heat or oxidation CIBA SPECIALTY CHEMICALS CORP. 2003-10-09 US disclosed
US-6136900-A POLYDIHYDROPYRIDINES, HYDROTALCITES, ZEOLITES, DAWSONITES, MAGADIITES OR KENYAITES, DISACCHARIDE ALCOHOLS, STERICALLY HINDERED AMINES, AND AT LEAST ONE ZINC, ALUMINIUM OR LANTHANOID COMPOUND, WITCO VINYL ADDITIVES GMBH (DE) 2000-10-24 US disclosed
US-5002698-A Anti-Wear Agents, Extreme Pressure Additives CIBA-GEIGY CORPORATION (US) 1991-03-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040013619-A1 Heteroaryl substituted hydroxyphenyltriazine uv-absorbers CBR1, CYP4Z1, CYP1A1 JAK2 4175/4885LMNA 810/4885GAA 3902/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.