SCHEMBL4860013

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4868666	0.91	CYP1A2 (0.55)	CYP1A2CYP3A4CYP2D6CYP2C19TSHR
	SCHEMBL4861484	0.89	CYP1A2 (0.64)	CYP1A2CYP3A4CYP2D6CYP2C19TSHR
	SCHEMBL5100860	0.88	CYP1A2 (0.67)	CYP1A2CYP3A4CYP2D6CYP2C19TSHR
	SCHEMBL5101338	0.88	CYP1A2 (0.56)	CYP1A2CYP3A4CYP2D6CYP2C19TSHR
	SCHEMBL4859455	0.85	CYP1A2 (0.65)	CYP1A2CYP3A4CYP2D6CYP2C19TSHR
	SCHEMBL4859221	0.82	ACHE (0.74)	KMT2AMEN1ACHEBCHE
	SCHEMBL4866399	0.82	CYP1A2 (0.50)	CYP1A2CYP3A4CYP2D6CYP2C19TSHR
	SCHEMBL5104517	0.82	ACHE (0.58)	CYP1A2CYP3A4CYP2D6CYP2C19TSHR
	SCHEMBL3113286	0.81	CYP1A2 (0.70)	CYP1A2CYP3A4CYP2D6CYP2C19TSHR
	SCHEMBL4861426	0.81	CYP1A2 (0.54)	CYP1A2CYP3A4CYP2D6CYP2C19TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.