SCHEMBL4860029

SCHEMBL4860029

C=C(C)C(=O)OC(C)N1C(=O)C2=C(CCCC2)C1=O

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.34
ATM Q13315 1/20 0.34
TSHR P16473 1/20 0.33
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11064065 0.81 TSHR (0.36) KMT2AATMTSHRALDH1A1
SCHEMBL2036449 0.81 KMT2A (0.43) KMT2AATMTSHRALDH1A1
SCHEMBL1147828 0.77 TSHR (0.33) TSHR
SCHEMBL2030887 0.76 LMNA (0.46) KMT2AALDH1A1
SCHEMBL19145906 0.75 LMNA (0.39) KMT2AATMTSHR
SCHEMBL4154528 0.74 LMNA (0.44) KMT2AATMTSHRALDH1A1
SCHEMBL12098030 0.73 SMN1; SMN2 (0.36) KMT2ATSHRALDH1A1
SCHEMBL8578110 0.72 TSHR (0.39) KMT2AATMTSHRALDH1A1
SCHEMBL5849387 0.71 CSNK2A2 (0.36) KMT2ATSHRALDH1A1
SCHEMBL4864684 0.71 TSHR (0.37) KMT2AATMTSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7320854-B2 Mixture of oxide particles, polymerizable compound,radiation sensitive decomposer and releasing agent JSR CORPORATION (JP) 2008-01-22 US disclosed
EP-1494072-A2 Radiation sensitive refractive index changing composition, pattern forming method and optical material JSR Corporation (JP) 2005-01-05 EP disclosed
US-20040265737-A1 Radiation sensitive refractive index changing composition, pattern forming method and optical material JSR CORPORATION (JP) 2004-12-30 US disclosed