SCHEMBL5849387

SCHEMBL5849387

C=C(C(=O)O)C(C)N1C(=O)C2=C(CCCC2)C1=O

nearest known ligand 0.36

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CSNK2A2 P19784 1/20 0.36
CSNK2B P67870 1/20 0.36
CSNK2A1 P68400 1/20 0.36
HTT P42858 2/20 0.33
LMNA P02545 1/20 0.33
ALDH1A1 P00352 1/20 0.33
MAPT P10636 1/20 0.31
TSHR P16473 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9502955 0.74 LMNA (0.63) HTTLMNAALDH1A1MAPTTSHR
SCHEMBL10107048 0.72 KDM4E (0.32) LMNA
SCHEMBL4860029 0.71 KMT2A (0.34) ALDH1A1TSHRKMT2A
SCHEMBL15394429 0.70 RXFP1 (0.33) HTTLMNAALDH1A1MAPTTSHR
SCHEMBL1147828 0.68 TSHR (0.33) TSHR
SCHEMBL5712749 0.67 ALDH1A1 (0.41) ALDH1A1MEN1KMT2A
SCHEMBL11037759 0.66 ALDH1A1 (0.41) ALDH1A1MEN1KMT2A
SCHEMBL27608814 0.63 KDM4E (0.36) LMNA
SCHEMBL5849379 0.63 KDM4E (0.38) LMNAALDH1A1TSHRKMT2A
SCHEMBL924888 0.62 LMNA (0.32) LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7084186-B2 Crosslinkable resin compositions TOAGOSEI CO., LTD. (JP) 2006-08-01 US disclosed
US-20020028302-A1 Crosslinkable resin compositions TOAGOSEI CO. LTD. 2002-03-07 US disclosed