SCHEMBL6912224

SCHEMBL6912224

CCCSc1cc(C)c(N)c(SCCC)c1N

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.34
CYP1A2 P05177 1/20 0.33
ALDH1A1 P00352 4/20 0.32
TP53 P04637 1/20 0.32
CYP3A4 P08684 1/20 0.32
TSHR P16473 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
MAPT P10636 2/20 0.32
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA7 P43166 1/20 0.32
CA9 Q16790 1/20 0.32
CA13 Q8N1Q1 1/20 0.32
HASPIN Q8TF76 1/20 0.31
HPGD P15428 2/20 0.31
KDM4E B2RXH2 1/20 0.31
TLR8 Q9NR97 1/20 0.30
HTT P42858 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6909728 0.89 TLR8 (0.41) ALDH1A1MAPTHASPINHPGDKDM4E
SCHEMBL48603 0.81 ALDH1A1 (0.34) ALDH1A1TP53CYP3A4TSHRTDP1
SCHEMBL5522764 0.76 ALDH1A1 (0.33) ALDH1A1TP53CYP3A4TSHRTDP1
SCHEMBL6905535 0.76 KMT2A (0.38) KMT2ACYP1A2ALDH1A1MAPTCA12
SCHEMBL10839342 0.75 MAPT (0.36) ALDH1A1TP53CYP3A4TSHRTDP1
SCHEMBL6911477 0.74 ALDH1A1 (0.32) ALDH1A1TP53CYP3A4TSHRTDP1
SCHEMBL8764562 0.74 ALDH1A1 (0.32) ALDH1A1TP53CYP3A4TSHRTDP1
SCHEMBL8764612 0.73
SCHEMBL1797285 0.71
SCHEMBL9184128 0.71 ALDH1A1 (0.40) ALDH1A1TP53CYP3A4TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9586446-B2 Ballistic resilient run-flat tire, kit and method thereof ACCELLA POLYURETHANE SYSTEMS LLC (US) 2017-03-07 US claimed
US-20160361956-A1 BALLISTIC RESILIENT RUN-FLAT TIRE, KIT AND METHOD THEREOF ACCELLA POLYURETHANE SYSTEMS LLC 2016-12-15 US claimed
EP-2819855-A1 BALLISTIC RESILIENT RUN-FLAT TIRE, KIT AND METHOD THEREOF Arnco, Inc. (US) 2015-01-07 EP claimed
WO-2013130113-A1 BALLISTIC RESILIENT RUN-FLAT TIRE, KIT AND METHOD THEREOF ARNCO (US) 2013-09-06 WO claimed
US-20130220507-A1 BALLISTIC RESILIENT RUN-FLAT TIRE, KIT AND METHOD THEREOF ARNCO (US) 2013-08-29 US claimed
EP-0635034-B1 POLYURETHANE ELASTOMER AND NON-PNEUMATIC TIRE FABRICATED THEREFROM UNIROYAL CHEM CO INC (US) 1997-07-30 EP claimed
EP-0635034-A1 POLYURETHANE ELASTOMER AND NON-PNEUMATIC TIRE FABRICATED THEREFROM. UNIROYAL CHEM CO INC (US) 1995-01-25 EP claimed
WO-1993021247-A1 POLYURETHANE ELASTOMER AND NON-PNEUMATIC TIRE FABRICATED THEREFROM UNIROYAL CHEMICAL COMPANY, INC. (US) 1993-10-28 WO claimed
US-9586446-B2 Ballistic resilient run-flat tire, kit and method thereof ACCELLA POLYURETHANE SYSTEMS LLC (US) 2017-03-07 US disclosed
US-20160361956-A1 BALLISTIC RESILIENT RUN-FLAT TIRE, KIT AND METHOD THEREOF ACCELLA POLYURETHANE SYSTEMS LLC 2016-12-15 US disclosed
EP-2819855-A1 BALLISTIC RESILIENT RUN-FLAT TIRE, KIT AND METHOD THEREOF Arnco, Inc. (US) 2015-01-07 EP disclosed
US-8821663-B2 Ballistic resilient run-flat tire, kit and method thereof ARNCO (US) 2014-09-02 US disclosed
WO-2013130113-A1 BALLISTIC RESILIENT RUN-FLAT TIRE, KIT AND METHOD THEREOF ARNCO (US) 2013-09-06 WO disclosed
US-20130220507-A1 BALLISTIC RESILIENT RUN-FLAT TIRE, KIT AND METHOD THEREOF ARNCO (US) 2013-08-29 US disclosed
US-6509434-B1 Condensation polymerization of alkylthiated mononuclear aromatic amines and isocyanate prepolymer to produce polyurethanes, polyureaurethanes and/or polyureas ALBEMARLE CORPORATION 2003-01-21 US disclosed
EP-0635034-B1 POLYURETHANE ELASTOMER AND NON-PNEUMATIC TIRE FABRICATED THEREFROM UNIROYAL CHEM CO INC (US) 1997-07-30 EP disclosed
EP-0635034-A1 POLYURETHANE ELASTOMER AND NON-PNEUMATIC TIRE FABRICATED THEREFROM. UNIROYAL CHEM CO INC (US) 1995-01-25 EP disclosed
WO-1993021247-A1 POLYURETHANE ELASTOMER AND NON-PNEUMATIC TIRE FABRICATED THEREFROM UNIROYAL CHEMICAL COMPANY, INC. (US) 1993-10-28 WO disclosed
US-5223599-A Polyetherurethanes and alkylthioaromatic amine curing agents, which are non-carcinogenic UNIROYAL CHEMICAL COMPANY, INC. (US) 1993-06-29 US disclosed
EP-0329821-A2 Polyhydroxyalkane/aromatic diamine chain extenders ETHYL CORPORATION (US) 1989-08-30 EP disclosed