SCHEMBL4860324

SCHEMBL4860324

C=CC(=O)OC12CC3CC(C1)CC(SCSc1ccccc1)(C3)C2

nearest known ligand 0.34

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
DPP8 Q6V1X1 16/20 0.34
DPP9 Q86TI2 16/20 0.34
GLMN Q92990 2/20 0.34
PKM P14618 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
DPP4 P27487 1/20 0.33
EPHX1 P07099 1/20 0.32
P2RX7 Q99572 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4866033 0.83 DPP8 (0.35) DPP8DPP9GLMNDPP4
SCHEMBL4863543 0.81 PKM (0.35) PKML3MBTL1
Phenyl Vinyl Sulfide SCHEMBL30733441 0.75 CYP19A1 (0.36) EPHX1P2RX7
SCHEMBL4863268 0.74 PKM (0.33) PKML3MBTL1
SCHEMBL822780 0.73 ALDH1A1 (0.36) DPP8DPP9GLMN
SCHEMBL4864687 0.72 DPP8 (0.33) DPP8DPP9GLMNP2RX7
SCHEMBL10483602 0.71 CYP17A1 (0.47) DPP8DPP9L3MBTL1
SCHEMBL4864920 0.71 THRB (0.33) P2RX7
SCHEMBL4856991 0.70 PKM (0.31) PKML3MBTL1
SCHEMBL4863639 0.70 MEN1 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7456311-B2 Adamantane derivative, process for producing the same, and photosensitive material for photoresist IDEMITSU KOSAN CO., LTD. (JP) 2008-11-25 US disclosed
US-20080009647-A1 Adamantane Derivative, Process for Producing the Same, and Photosensitive Material for Photoresist IDEMITSU KOSAN CO., LTD. (JP) 2008-01-10 US disclosed
EP-1803708-A1 ADAMANTANE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND PHOTOSENSITIVE MATERIAL FOR PHOTORESIST IDEMITSU KOSAN CO., LTD. (JP) 2007-07-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080009647-A1 Adamantane Derivative, Process for Producing the Same, and Photosensitive Material for Photoresist LSS, C1S, DHPS DPP8 4002/4885DPP9 3822/4885GLMN 4526/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.