Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.70 |
| ▸ | MAPT | P10636 | 3/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.70 |
| ▸ | POLB | P06746 | 1/20 | 0.70 |
| ▸ | BLM | P54132 | 1/20 | 0.70 |
| ▸ | ATM | Q13315 | 1/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.70 |
| ▸ | ALKBH5 | Q6P6C2 | 3/20 | 0.49 |
| ▸ | MAOA | P21397 | 4/20 | 0.47 |
| ▸ | MAOB | P27338 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MPI | P34949 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11478321 | 0.83 | ALKBH5 (0.66) | LMNAMAPTALDH1A1POLBBLM | |
| SCHEMBL761304 | 0.83 | MAPT (0.50) | LMNAMAPTALDH1A1POLBBLM | |
| SCHEMBL11483364 | 0.83 | ALKBH5 (0.54) | LMNAMAPTALDH1A1POLBBLM | |
| SCHEMBL7247120 | 0.82 | ALDH1A1 (1.00) | LMNAMAPTALDH1A1POLBBLM | |
| SCHEMBL11491891 | 0.79 | NOX4 (0.47) | LMNAMAPTALDH1A1POLBBLM | |
| SCHEMBL3529810 | 0.78 | MAPT (0.44) | LMNAMAPTALDH1A1POLBBLM | |
| SCHEMBL11484476 | 0.78 | ALDH1A1 (0.48) | LMNAMAPTALDH1A1POLBBLM | |
| SCHEMBL7234970 | 0.78 | MAPT (0.57) | LMNAMAPTALDH1A1POLBBLM | |
| SCHEMBL11478374 | 0.78 | MAPT (0.48) | LMNAMAPTALDH1A1POLBBLM | |
| SCHEMBL11189675 | 0.77 | MAPT (0.62) | LMNAMAPTALDH1A1POLBBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119064341-A | Color reusable time temperature indicator and preparation method thereof | 四川大学 | 2024-12-03 | — | — | CN | claimed |
| CN-118530180-A | Di-heterocyclic compound containing trifluoromethyl pyrazolone and amino pyrazole skeleton and preparation thereof | 上海大学 | 2024-08-23 | — | — | CN | claimed |
| CN-119064341-A | Color reusable time temperature indicator and preparation method thereof | 四川大学 | 2024-12-03 | — | — | CN | disclosed |
| CN-118530180-A | Di-heterocyclic compound containing trifluoromethyl pyrazolone and amino pyrazole skeleton and preparation thereof | 上海大学 | 2024-08-23 | — | — | CN | disclosed |
| CN-118530180-A | Di-heterocyclic compound containing trifluoromethyl pyrazolone and amino pyrazole skeleton and preparation thereof | 上海大学 | 2024-08-23 | — | — | CN | disclosed |
| CN-114933593-A | Multi-heterocyclic compound containing trifluoromethyl pyrazolone structural unit, preparation method and application thereof | 上海大学 | 2022-08-23 | — | — | CN | disclosed |
| CN-110128345-A | A kind of preparation method of e derivatives | 上海大学 | 2019-08-16 | — | — | CN | disclosed |
| CN-103951663-B | Containing replacing the pyrazole amide of 1,3,4-thiadiazoles thioether and pyrazole imine analog derivative and preparation method and application | 贵州大学 | 2016-08-17 | — | — | CN | disclosed |
| CN-103613583-B | 1,3-substituting group-4-substituted pyrazolecarboxylic acylhydrazone and its preparation method and application | GUIZHOU UNIVERSITY (CN) | 2015-12-02 | — | — | CN | disclosed |
| EP-2145884-B1 | INDOLEDIONE DERIVATIVE | MSD KK (JP) | 2014-08-06 | — | — | EP | disclosed |
| CN-103951663-A | Pyrazole amide and pyrazole imine derivatives containing substituted 1, 3, 4-thiadiazole thioether as well as preparation method and application of derivatives | UNIV GUIZHOU | 2014-07-30 | — | — | CN | disclosed |
| US-6660867-B2 | Squarylium compounds having spectroscopic properties, light resistance, solubility and thermal decomposition properties suitable for a recording material for DVD-R, and optical recording media using the same | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2003-12-09 | — | — | US | disclosed |
| US-20030187272-A1 | Metal complex type squarylium compounds and optical recording media made by using the same | KYOWA HAKKO CHEMICAL CO., LTD. (FORMERLY KYOWA YUKA CO., LTD.) (JP) | 2003-10-02 | — | — | US | disclosed |
| EP-1334998-A1 | METAL COMPLEX TYPE SQUARYLIUM COMPOUNDS AND OPTICAL RECORDING MEDIA MADE BY USING THE SAME | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2003-08-13 | — | — | EP | disclosed |
| US-6107487-A | FREE OF WATER-SOLUBILIZING GROUPS; SUITABLE FOR THERMAL DYE TRANSFER AND FOR DYEING AND PRINTING SYNTHETIC MATERIALS | BASF AKTIENGESELLSCHAFT (DE) | 2000-08-22 | — | — | US | disclosed |
| US-5677283-A | α-heteroaryloxymethyl ketones as interleukin - 1 β converting enzyme inhibitors | SANOFI (FR) | 1997-10-14 | — | — | US | disclosed |
| US-5585357-A | Heteroaryloxymethyl ketones as interleukin-1βconverting enzyme inhibitors | SANOFI WINTHROP INC. (US) | 1996-12-17 | — | — | US | disclosed |
| EP-0644198-A1 | Alpha-heteroaryloxymethyl ketones as interleukin-1beta converting enzyme inhibitors | STERLING WINTHROP INC. (US) | 1995-03-22 | — | — | EP | disclosed |
| US-4440852-A | Silver halide photographic light-sensitive material containing oxonal dyes | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1984-04-03 | — | — | US | disclosed |
| US-4212647-A | Water-insoluble azo dyestuffs which are derivatives of 1-aryl-3-trifluoromethyl-5-pyrazolones | PRODUITS CHIMIQUES UGINE KUHLMANN (FR) | 1980-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030187272-A1 | Metal complex type squarylium compounds and optical recording media made by using the same | DCLK2, DCLK3, DCLK1 | LMNA 2752/4885MAPT 3668/4885ALDH1A1 2113/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.