Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | ATM | Q13315 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | CNR2 | P34972 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CNR1 | P21554 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formic Acid SCHEMBL27713038 | 0.96 | PIN1 (0.42) | RAB9AATML3MBTL1KDM4EGAA | |
| SCHEMBL485671 | 0.88 | KDM4E (0.48) | RAB9AKDM4ELMNAALDH1A1MEN1 | |
| Formic Acid SCHEMBL27713042 | 0.85 | SCN9A (0.43) | RAB9AATML3MBTL1KDM4EGAA | |
| SCHEMBL485245 | 0.82 | CXCR2 (0.58) | RAB9AATML3MBTL1KDM4EGAA | |
| SCHEMBL485572 | 0.82 | CXCR2 (0.51) | RAB9AATML3MBTL1KDM4EGAA | |
| SCHEMBL27713037 | 0.81 | CXCR2 (0.44) | RAB9AATML3MBTL1KDM4EGAA | |
| Formic Acid SCHEMBL27693263 | 0.80 | MEN1 (0.57) | RAB9AL3MBTL1KDM4EALDH1A1MEN1 | |
| SCHEMBL10289497 | 0.78 | RAB9A (0.44) | RAB9AATML3MBTL1KDM4EGAA | |
| Formic Acid SCHEMBL27693208 | 0.78 | ALOX5AP (0.51) | RAB9AKDM4EGAALMNAALDH1A1 | |
| SCHEMBL485544 | 0.76 | CXCR2 (0.46) | RAB9AATML3MBTL1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1836158-B1 | FUSED BICYCLIC CARBOXAMIDE DERIVATIVES FOR USE AS CXCR2 INHIBITORS IN THE TREATMENT OF INFLAMMATION | SANOFI AVENTIS DEUTSCHLAND (DE) | 2012-02-01 | — | — | EP | claimed |