Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 3/20 | 0.38 |
| ▸ | GABRD | O14764 | 3/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.38 |
| ▸ | GABRE | P78334 | 3/20 | 0.38 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.38 |
| ▸ | GABRG1 | Q8N1C3 | 3/20 | 0.38 |
| ▸ | GABRG3 | Q99928 | 3/20 | 0.38 |
| ▸ | GABRQ | Q9UN88 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14017806 | 0.83 | SLC6A12 (0.33) | LMNAGRM2SLC6A12ALDH1A1 | |
| SCHEMBL4859086 | 0.81 | GRM2 (0.36) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL5383949 | 0.75 | CYP2D6 (0.39) | LMNACYP2D6CYP2C19CYP2C9KMT2A | |
| SCHEMBL524642 | 0.71 | GABRP (0.69) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL4853073 | 0.69 | TUBB4A (0.41) | LMNAKMT2APOLBGRM2KDM4E | |
| Hydrochloric Acid SCHEMBL10515638 | 0.68 | GABRP (0.37) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL8916010 | 0.68 | POLB (0.60) | LMNACYP2D6CYP2C19CYP2C9KMT2A | |
| SCHEMBL1969600 | 0.66 | GABRP (0.72) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL20293716 | 0.66 | P4HTM (0.48) | LMNACYP2D6CYP2C19CYP2C9KMT2A | |
| SCHEMBL2518980 | 0.65 | GABRP (0.50) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7439207-B2 | 2,6 substituted pyridine-3-carbonyl derivatives serving as plant protection agents having herbicidal action | BAYER CROPSCIENCE AG (DE) | 2008-10-21 | — | — | US | disclosed |
| US-7439207-B2 | 2,6 substituted pyridine-3-carbonyl derivatives serving as plant protection agents having herbicidal action | BAYER CROPSCIENCE AG (DE) | 2008-10-21 | — | — | US | disclosed |
| US-7439207-B2 | 2,6 substituted pyridine-3-carbonyl derivatives serving as plant protection agents having herbicidal action | BAYER CROPSCIENCE AG (DE) | 2008-10-21 | — | — | US | disclosed |
| EP-1501360-A1 | 2,6 SUBSTITUTED PYRIDINE-3-CARBONYL DERIVATIVES SERVING AS PLANT PROTECTION AGENTS HAVING HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2005-02-02 | — | — | EP | disclosed |
| US-20050020451-A1 | 2,6 Substituted pyridine-3-carbonyl derivatives serving as plant protection agents having herbicidal action | BAYER CROPSCIENCE AG (DE) | 2005-01-27 | — | — | US | disclosed |
| WO-2003092380-A1 | 2,6 SUBSTITUTED PYRIDINE-3-CARBONYL DERIVATIVES SERVING AS PLANT PROTECTION AGENTS HAVING HERBICIDAL ACTION | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2003-11-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050020451-A1 | 2,6 Substituted pyridine-3-carbonyl derivatives serving as plant protection agents having herbicidal action | PDHX, PRDX6, CBR3 | GABRP 2428/4885GABRD 3440/4885GABRA1 3486/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.