Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 1/20 | 0.47 |
| ▸ | PTAFR | P25105 | 4/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 7/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.42 |
| ▸ | ITGAV | P06756 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4861471 | 1.00 | NPY5R (0.47) | NPY5RPTAFREPHX2MMP2MMP9 | |
| SCHEMBL4857259 | 0.84 | NPY5R (0.62) | NPY5RMMP2MMP9 | |
| SCHEMBL4858174 | 0.84 | MMP2 (0.56) | NPY5RMMP2MMP9 | |
| SCHEMBL4857262 | 0.84 | NPY5R (0.62) | NPY5RMMP2MMP9 | |
| SCHEMBL4858181 | 0.84 | MMP2 (0.56) | NPY5RMMP2MMP9 | |
| SCHEMBL3735521 | 0.84 | PTAFR (0.44) | NPY5RPTAFREPHX2NAMPTTBXAS1 | |
| SCHEMBL3735516 | 0.84 | PTAFR (0.44) | NPY5RPTAFREPHX2NAMPTTBXAS1 | |
| SCHEMBL4863198 | 0.83 | KMT2A (0.44) | NPY5RMMP2MMP9 | |
| SCHEMBL4863204 | 0.83 | KMT2A (0.44) | NPY5RMMP2MMP9 | |
| SCHEMBL4865492 | 0.83 | NPY5R (0.45) | NPY5RMMP2MMP9ITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2008520575-A | — | — | 2008-06-19 | — | — | JP | claimed |
| EP-1812012-A2 | PROTEIN TYROSINE PHOSPHATASE INHIBITORS AND METHODS OF USE THEREOF | Ceptyr, Inc. (US) | 2007-08-01 | — | — | EP | claimed |
| WO-2006055525-A2 | PROTEIN TYROSINE PHOSPHATASE INHIBITORS AND METHODS OF USE THEREOF | CEPTYR, INC. (US) | 2006-05-26 | — | — | WO | claimed |
| EP-1812012-A2 | PROTEIN TYROSINE PHOSPHATASE INHIBITORS AND METHODS OF USE THEREOF | Ceptyr, Inc. (US) | 2007-08-01 | — | — | EP | disclosed |
| WO-2006055525-A2 | PROTEIN TYROSINE PHOSPHATASE INHIBITORS AND METHODS OF USE THEREOF | CEPTYR, INC. (US) | 2006-05-26 | — | — | WO | disclosed |