Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4863198 | 1.00 | KMT2A (0.44) | KMT2ANPY5RLMNASMN1; SMN2MMP8 | |
| SCHEMBL3741457 | 0.83 | PTPN1 (0.44) | KMT2ANPY5R | |
| SCHEMBL3741458 | 0.83 | PTPN1 (0.44) | KMT2ANPY5R | |
| SCHEMBL4861466 | 0.83 | NPY5R (0.47) | NPY5RMMP2MMP9 | |
| SCHEMBL4861471 | 0.83 | NPY5R (0.47) | NPY5RMMP2MMP9 | |
| SCHEMBL4858174 | 0.82 | MMP2 (0.56) | NPY5RMMP2MMP9CNR1 | |
| SCHEMBL4857262 | 0.82 | NPY5R (0.62) | NPY5RLMNASMN1; SMN2HTTMMP2 | |
| SCHEMBL4857259 | 0.82 | NPY5R (0.62) | NPY5RLMNASMN1; SMN2HTTMMP2 | |
| SCHEMBL4858181 | 0.82 | MMP2 (0.56) | NPY5RMMP2MMP9CNR1 | |
| SCHEMBL3741460 | 0.81 | SRC (0.47) | KMT2ANPY5RLMNASMN1; SMN2MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2008520575-A | — | — | 2008-06-19 | — | — | JP | claimed |
| EP-1812012-A2 | PROTEIN TYROSINE PHOSPHATASE INHIBITORS AND METHODS OF USE THEREOF | Ceptyr, Inc. (US) | 2007-08-01 | — | — | EP | claimed |
| WO-2006055525-A2 | PROTEIN TYROSINE PHOSPHATASE INHIBITORS AND METHODS OF USE THEREOF | CEPTYR, INC. (US) | 2006-05-26 | — | — | WO | claimed |