Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 2/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | GRM8 | O00222 | 1/20 | 0.31 |
| ▸ | GRM6 | O15303 | 1/20 | 0.31 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.31 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.31 |
| ▸ | GSR | P00390 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.31 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1654337 | 0.87 | LTA4H (0.43) | LTA4HNOS1NOS3NOS2SLC1A1 | |
| SCHEMBL18477 | 0.87 | LTA4H (0.43) | LTA4HNOS1NOS3NOS2SLC1A1 | |
| SCHEMBL1841835 | 0.87 | LTA4H (0.43) | LTA4HNOS1NOS3NOS2SLC1A1 | |
| SCHEMBL31229195 | 0.86 | L3MBTL1 (0.39) | LTA4HNOS1NOS3NOS2SLC1A1 | |
| SCHEMBL7011445 | 0.86 | L3MBTL1 (0.39) | LTA4HNOS1NOS3NOS2SLC1A1 | |
| SCHEMBL5326417 | 0.86 | L3MBTL1 (0.39) | LTA4HNOS1NOS3NOS2SLC1A1 | |
| Hydrochloric Acid SCHEMBL1517836 | 0.86 | LTA4H (0.42) | LTA4HNOS1NOS3NOS2SLC1A1 | |
| Water SCHEMBL3912787 | 0.86 | LTA4H (0.42) | LTA4HNOS1NOS3NOS2SLC1A1 | |
| SCHEMBL6893763 | 0.86 | LTA4H (0.42) | LTA4HNOS1NOS3NOS2SLC1A1 | |
| Hydrochloric Acid SCHEMBL4654220 | 0.86 | LTA4H (0.42) | LTA4HNOS1NOS3NOS2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7396859-B2 | Perturbed membrane-binding compounds | NST NEUROSURVIVAL TECHNOLOGIES, LTD. (IL) | 2008-07-08 | — | — | US | disclosed |
| US-20040082499-A1 | Perturbed membrane-binding compounds | APOSENSE LTD. (IL) | 2004-04-29 | — | — | US | disclosed |
| EP-1401420-A2 | PERTURBED MEMBRANE-BINDING COMPOUNDS | NST Neurosurvival Technologies Ltd. (IL) | 2004-03-31 | — | — | EP | disclosed |
| WO-2002046147-A2 | PERTURBED MEMBRANE-BINDING COMPOUNDS | NST NEUROSURVIVAL TECHNOLOGIES LTD. (IL) | 2002-06-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040082499-A1 | Perturbed membrane-binding compounds | PEBP1, VAPB, MBOAT1 | LTA4H 3545/4885NOS1 4876/4885NOS3 4868/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.