SCHEMBL486168

SCHEMBL486168

C=C(C)C(=O)OCCCCC([SiH3])(OCC)OCC

nearest known ligand 0.56

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.56
THRB P10828 2/20 0.49
HTT P42858 2/20 0.40
POLB P06746 1/20 0.40
APEX1 P27695 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
ALDH1A1 P00352 3/20 0.33
PKM P14618 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21066701 0.98 TSHR (0.58) TSHRTHRBHTTPOLBAPEX1
SCHEMBL21066735 0.98 TSHR (0.58) TSHRTHRBHTTPOLBAPEX1
SCHEMBL986236 0.95 TSHR (0.53) TSHRTHRBHTTPOLBAPEX1
SCHEMBL17922843 0.89 THRB (0.53) TSHRTHRBHTTPOLBAPEX1
SCHEMBL4441169 0.84 TSHR (0.56) TSHRTHRBHTTPOLBAPEX1
SCHEMBL28396649 0.84 TSHR (0.54) TSHRTHRBHTTPOLBAPEX1
SCHEMBL23923096 0.83 TSHR (0.57) TSHRTHRBHTTPOLBAPEX1
SCHEMBL1024052 0.83 TSHR (0.57) TSHRTHRBHTTPOLBAPEX1
SCHEMBL21066702 0.83 TSHR (0.57) TSHRTHRBHTTPOLBAPEX1
SCHEMBL21066745 0.83 TSHR (0.57) TSHRTHRBHTTPOLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 285 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118221883-A Multilayer core-shell structure polymer and preparation method and application thereof 中化学科学技术研究有限公司 2024-06-21 CN claimed
CN-115181223-A Low-gloss matte auxiliary agent, preparation method thereof and formed body 铨盛聚碳科技股份有限公司 2022-10-14 CN claimed
CN-106866971-B Weather-resistant low-temperature-resistant organic silicon impact modifier and preparation method and application thereof 广东优科艾迪高分子材料有限公司 2020-05-05 CN claimed
US-6281297-B1 CONTAINING ALLYL METHACRYLATE AND ORGANOSILICON COMPOUND KANEKA CORPORATION (JP) 2001-08-28 US claimed
US-20240158904-A1 UNDERCOAT AGENT COMPOSITION FOR LAYERING INORGANIC MATERIAL LAYER, CURED PRODUCT THEREOF AND PRODUCTION METHOD THEREOF TOAGOSEI CO., LTD. (JP) 2024-05-16 US disclosed
US-11976189-B2 Thermoplastic resin composition and molded article TECHNO-UMG CO., LTD. (JP) 2024-05-07 US disclosed
US-20240052165-A1 RESIN COMPOSITION AND MOLDED BODY MITSUBISHI CHEMICAL CORPORATION (JP) 2024-02-15 US disclosed
US-20240043678-A1 THERMOPLASTIC RESIN COMPOSITION AND MOLDED ARTICLE TECHNO-UMG CO., LTD. (JP) 2024-02-08 US disclosed
EP-4317310-A1 THERMOPLASTIC RESIN COMPOSITION AND MOLDED ARTICLE Techno-UMG Co., Ltd. (JP) 2024-02-07 EP disclosed
EP-4317229-A1 POLYORGANOSILOXANE-CONTAINING POLYMER, COMPOSITION, AND MOLDED ARTICLE Mitsubishi Chemical Corporation (JP) 2024-02-07 EP disclosed
EP-4317309-A1 THERMOPLASTIC RESIN COMPOSITION AND MOLDED ARTICLE THEREOF Techno-UMG Co., Ltd. (JP) 2024-02-07 EP disclosed
EP-4317325-A1 RESIN COMPOSITION AND MOLDED BODY Mitsubishi Chemical Corporation (JP) 2024-02-07 EP disclosed
US-4892900-A CONTAINING POLYSILOXANE GRAFT POLYMER, IMPROVED IMPACT STRENGTH MITSUBISHI RAYON CO., LTD. (JP) 1990-01-09 US disclosed
US-4888388-A BLENDS WITH POLYESTERS AND GRAFTED POLYSILOXANE-ACRYLIC POLYMERS MITSUBISHI RAYON COMPANY LIMITED (JP) 1989-12-19 US disclosed
EP-0326038-A1 An impact-resistant resin composition MITSUBISHI RAYON CO., LTD. (JP) 1989-08-02 EP disclosed
EP-0308871-A2 Thermoplastic polyester resin composition MITSUBISHI RAYON CO., LTD. (JP) 1989-03-29 EP disclosed
US-4775712-A BLENDS WITH POLYSILOXANES-IMPACT STRENGTH, HEAT AND COLD RESISTANT, WEATHERPROOFING-MOLDING MATERIALS MITSUBISHI RAYON CO., LTD. (JP) 1988-10-04 US disclosed
EP-0260552-A2 Graft copolymer rubber and polyphenylene ether resin composition comprising this rubber. MITSUBISHI RAYON CO., LTD. (JP) 1988-03-23 EP disclosed
US-4690986-A Impact-resistant thermoplastic polyorganosiloxane-based graft copolymer and process for producing same MITSUBISHI RAYON CO., LTD. (JP) 1987-09-01 US disclosed
EP-0231776-A1 Thermoplastic polyester resin composition MITSUBISHI RAYON CO., LTD. (JP) 1987-08-12 EP disclosed