SCHEMBL1024052

SCHEMBL1024052

C=C(C)C(=O)OCCCCCCCCCCCC([SiH3])(OC)OC

nearest known ligand 0.57

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.57
POLB P06746 1/20 0.44
APEX1 P27695 1/20 0.44
HTT P42858 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
THRB P10828 1/20 0.42
ALDH1A1 P00352 3/20 0.35
CYP3A4 P08684 1/20 0.32
NAAA Q02083 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21066745 1.00 TSHR (0.57) TSHRPOLBAPEX1HTTTDP1
SCHEMBL23923096 1.00 TSHR (0.57) TSHRPOLBAPEX1HTTTDP1
SCHEMBL26918774 1.00 TSHR (0.57) TSHRPOLBAPEX1HTTTDP1
SCHEMBL21066702 1.00 TSHR (0.57) TSHRPOLBAPEX1HTTTDP1
SCHEMBL28396649 0.98 TSHR (0.54) TSHRPOLBAPEX1HTTTDP1
SCHEMBL419928 0.93 TSHR (0.51) TSHRPOLBAPEX1HTTTDP1
SCHEMBL734093 0.86 THRB (0.47) TSHRPOLBAPEX1HTTTDP1
SCHEMBL21066701 0.84 TSHR (0.58) TSHRPOLBAPEX1HTTTDP1
SCHEMBL21066735 0.84 TSHR (0.58) TSHRPOLBAPEX1HTTTDP1
SCHEMBL9469051 0.83 TSHR (0.45) TSHRPOLBAPEX1HTTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3669854-B1 PHOTOPOLYMERIZABLE DENTAL COMPOSITION G C DENTAL IND CORP (JP) 2026-04-08 EP disclosed
WO-2025126917-A1 DENTAL COMPOSITION クラレノリタケデンタル株式会社 2025-06-19 WO disclosed
EP-3586814-B1 DENTAL CURABLE COMPOSITION G C DENTAL IND CORP (JP) 2024-01-31 EP disclosed
US-20220313564-A1 DENTAL RESTORATION COMPOSITE RESIN GC CORPORATION (JP) 2022-10-06 US disclosed
US-11446214-B2 Curable dental composite GC CORPORATION (JP) 2022-09-20 US disclosed
EP-4018993-A1 DENTAL RESTORATION COMPOSITE RESIN GC Corporation (JP) 2022-06-29 EP disclosed
CN-113677309-A Two-component curable dental composition 株式会社GC 2021-11-19 CN disclosed
US-11135137-B2 Dental photopolymerizable composition GC CORPORATION (JP) 2021-10-05 US disclosed
EP-3865110-A1 DENTAL RESTORATION COMPOSITE RESIN GC Corporation (JP) 2021-08-18 EP disclosed
US-20210244626-A1 DENTAL RESTORATION COMPOSITE RESIN GC CORPORATION (JP) 2021-08-12 US disclosed
EP-3381435-A2 DENTAL ADHESIVE AGENT AND METHOD OF MANUFACTURING THEREOF GC Corporation (JP) 2018-10-03 EP disclosed
US-20180049953-A1 DENTAL CURABLE COMPOSITION AND METHOD OF MANUFACTURING SAME GC CORPORATION (JP) 2018-02-22 US disclosed
EP-3272325-A1 CURABLE COMPOSITION FOR DENTAL USE AND METHOD FOR MANUFACTURING SAME GC Corporation (JP) 2018-01-24 EP disclosed
US-9855196-B2 Dental curable composition and dental flowable composite resin KURARAY NORITAKE DENTAL INC. (JP) 2018-01-02 US disclosed
EP-2275076-B1 DENTAL COMPOSITION AND COMPOSITE RESIN KURARAY NORITAKE DENTAL INC (JP) 2017-03-01 EP disclosed
US-20150320646-A1 DENTAL CURABLE COMPOSITION AND DENTAL FLOWABLE COMPOSITE RESIN KURARAY NORITAKE DENTAL INC. (JP) 2015-11-12 US disclosed
EP-2926796-A1 DENTAL CURABLE COMPOSITION AND DENTAL FLOWABLE COMPOSITE RESIN Kuraray Noritake Dental Inc. (JP) 2015-10-07 EP disclosed
US-8455564-B2 Dental composition and composite resin KURARAY NORITAKE DENTAL INC. (JP) 2013-06-04 US disclosed
US-20110046261-A1 DENTAL COMPOSITION AND COMPOSITE RESIN KURARAY MEDICAL INC. (JP) 2011-02-24 US disclosed
EP-2275076-A1 DENTAL COMPOSITION AND COMPOSITE RESIN Kuraray Medical Inc. (JP) 2011-01-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180049953-A1 DENTAL CURABLE COMPOSITION AND METHOD OF MANUFACTURING SAME SEM1, PSMC6, PSMB1 TSHR 2539/4885POLB 296/4885APEX1 3697/4885
US-20220313564-A1 DENTAL RESTORATION COMPOSITE RESIN ARCN1, COG1, SEM1 TSHR 3773/4885POLB 772/4885APEX1 2102/4885
US-20210244626-A1 DENTAL RESTORATION COMPOSITE RESIN COG1, ARCN1, PSMA1 TSHR 3715/4885POLB 699/4885APEX1 2152/4885
US-11135137-B2 Dental photopolymerizable composition ALAD, HTT, PPA1 TSHR 2336/4885POLB 950/4885APEX1 844/4885
US-20110046261-A1 DENTAL COMPOSITION AND COMPOSITE RESIN CAD, KATNAL2, ZYX TSHR 3309/4885POLB 623/4885APEX1 4096/4885
US-11446214-B2 Curable dental composite VCL, CORO1A, ACTB TSHR 3573/4885POLB 588/4885APEX1 3501/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.