Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 9/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 2/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1243985 | 0.92 | PDE10A (0.38) | ALDH1A1PDE10ALMNATSHRMEN1 | |
| SCHEMBL14922515 | 0.91 | GPR119 (0.34) | ALDH1A1PDE10ATSHR | |
| SCHEMBL2883439 | 0.91 | ALDH1A1 (0.33) | ALDH1A1PDE10ALMNATSHRMEN1 | |
| SCHEMBL2509026 | 0.88 | PDE10A (0.38) | ALDH1A1PDE10ALMNATSHRMEN1 | |
| SCHEMBL26209540 | 0.85 | KDM1A (0.38) | ALDH1A1LMNATSHRHTTHSD17B10 | |
| SCHEMBL26209563 | 0.85 | KDM1A (0.38) | ALDH1A1LMNATSHRHTTHSD17B10 | |
| SCHEMBL17827785 | 0.85 | KDM1A (0.38) | ALDH1A1LMNATSHRHTTHSD17B10 | |
| SCHEMBL17827780 | 0.85 | KDM1A (0.38) | ALDH1A1LMNATSHRHTTHSD17B10 | |
| SCHEMBL14389835 | 0.85 | LMNA (0.33) | ALDH1A1PDE10ALMNATSHRMEN1 | |
| SCHEMBL18712354 | 0.85 | SCN9A (0.33) | ALDH1A1HTTKDM1ACHRM4CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8580146-B2 | Liquid crystal compound, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-11-12 | — | — | US | disclosed |
| EP-1852429-B1 | Hexahydro dibenzofuran derivatives | MERCK PATENT GMBH (DE) | 2010-09-15 | — | — | EP | disclosed |
| US-7417157-B2 | Hexahydrodibenzofuran derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2008-08-26 | — | — | US | disclosed |