Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 9/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | FPR2 | P25090 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2509026 | 0.95 | PDE10A (0.38) | PDE10AALDH1A1TRPV3MEN1KMT2A | |
| SCHEMBL4861841 | 0.92 | ALDH1A1 (0.35) | PDE10AALDH1A1TRPV3MEN1KMT2A | |
| SCHEMBL424339 | 0.90 | GPR119 (0.36) | PDE10AALDH1A1TRPV3TSHRCHRM1 | |
| SCHEMBL10010236 | 0.88 | GPR119 (0.37) | PDE10AALDH1A1TRPV3MEN1KMT2A | |
| SCHEMBL11894480 | 0.86 | TRPV3 (0.33) | PDE10AALDH1A1TRPV3 | |
| SCHEMBL30209606 | 0.86 | PDE10A (0.35) | PDE10AALDH1A1TRPV3MEN1KMT2A | |
| SCHEMBL2883439 | 0.83 | ALDH1A1 (0.33) | PDE10AALDH1A1TRPV3MEN1KMT2A | |
| SCHEMBL14922515 | 0.83 | GPR119 (0.34) | PDE10AALDH1A1TSHRGPR119MAPT | |
| SCHEMBL18712372 | 0.83 | KDM1A (0.35) | ALDH1A1TRPV3HTTKDM1ACHRM4 | |
| SCHEMBL14922531 | 0.82 | KDM1A (0.41) | ALDH1A1LMNATSHRHTTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9109157-B2 | Liquid crystal compound having negative dielectric anisotropy, liquid crystal composition and liquid crystal display device using the same | JNC CORPORATION (JP) | 2015-08-18 | — | — | US | disclosed |
| US-9109157-B2 | Liquid crystal compound having negative dielectric anisotropy, liquid crystal composition and liquid crystal display device using the same | JNC CORPORATION (JP) | 2015-08-18 | — | — | US | disclosed |
| EP-2266941-B1 | TRICYCLIC LIQUID CRYSTALLINE COMPOUND HAVING LATERAL FLUORINE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | JNC CORP (JP) | 2014-03-05 | — | — | EP | disclosed |
| US-8580146-B2 | Liquid crystal compound, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-11-12 | — | — | US | disclosed |
| US-8580146-B2 | Liquid crystal compound, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2013-11-12 | — | — | US | disclosed |
| US-20120193577-A1 | LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | JNC PETROCHEMICAL CORPORATION (JP) | 2012-08-02 | — | — | US | disclosed |
| US-20120190897-A1 | LIQUID CRYSTAL COMPOUND HAVING NEGATIVE DIELECTRIC ANISOTROPY, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE USING THE SAME | JNC PETROCHEMICAL CORPORATION (JP) | 2012-07-26 | — | — | US | disclosed |
| US-20120190897-A1 | LIQUID CRYSTAL COMPOUND HAVING NEGATIVE DIELECTRIC ANISOTROPY, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE USING THE SAME | JNC PETROCHEMICAL CORPORATION (JP) | 2012-07-26 | — | — | US | disclosed |
| US-8216489-B2 | Three-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device | JNC CORPORATION (JP) | 2012-07-10 | — | — | US | disclosed |
| US-8216489-B2 | Three-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device | JNC CORPORATION (JP) | 2012-07-10 | — | — | US | disclosed |
| US-20110037024-A1 | THREE-RING LIQUID CRYSTAL COMPOUND HAVING LATERAL FLUORINE, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE | CHISSO CORPORATION (JP) | 2011-02-17 | — | — | US | disclosed |
| EP-2266941-A1 | TRICYCLIC LIQUID CRYSTALLINE COMPOUND HAVING LATERAL FLUORINE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | Chisso Corporation (JP) | 2010-12-29 | — | — | EP | disclosed |
| WO-2009125668-A1 | TRICYCLIC LIQUID CRYSTALLINE COMPOUND HAVING LATERAL FLUORINE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | チッソ株式会社 (JP) | 2009-10-15 | — | — | WO | disclosed |
| EP-1362839-B1 | Liquid crystal composition having a positive delta-epsilon and liquid crystal display device | CHISSO CORP (JP) | 2008-08-13 | — | — | EP | disclosed |
| US-7081279-B2 | Alkenyl compound having a negative Δε value, liquid crystal composition, and liquid crystal display device | CHISSO CORPORATION (JP) | 2006-07-25 | — | — | US | disclosed |
| US-20040065866-A1 | Alkenyl compound having a negative delta epsilon value, liquid crystal composition, and liquid crystal display device | CHISSO CORPORATION (JP) | 2004-04-08 | — | — | US | disclosed |
| US-6692657-B1 | ALKENYL COMPOUND WITH 2,3-DIFLUOROPHENYL GROUP | CHISSO CORPORATION (JP) | 2004-02-17 | — | — | US | disclosed |
| EP-1362839-A2 | Liquid crystal composition having a delta-epsilon- of not less than zero and liquid crystal display device | CHISSO CORPORATION (JP) | 2003-11-19 | — | — | EP | disclosed |
| EP-0969071-B1 | Alkenyl compound having a negative delta epsilon value, liquid crystal composition and liquid crystal display device | CHISSO CORP (JP) | 2003-11-05 | — | — | EP | disclosed |
| EP-0969071-A1 | Alkenyl compound having a negative delta epsilon value, liquid crystal composition and liquid crystal display device | CHISSO CORPORATION (JP) | 2000-01-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120190897-A1 | LIQUID CRYSTAL COMPOUND HAVING NEGATIVE DIELECTRIC ANISOTROPY, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE USING THE SAME | H1-0, EFHD2, CCND2 | PDE10A 2318/4885ALDH1A1 654/4885TRPV3 1157/4885 |
| US-20120193577-A1 | LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | KIF23, MARK3, CCND3 | PDE10A 1946/4885ALDH1A1 4082/4885TRPV3 5/4885 |
| US-20040065866-A1 | Alkenyl compound having a negative delta epsilon value, liquid crystal composition, and liquid crystal display device | CTNND1, CCT4, DLK1 | PDE10A 2804/4885ALDH1A1 1284/4885TRPV3 890/4885 |
| US-20110037024-A1 | THREE-RING LIQUID CRYSTAL COMPOUND HAVING LATERAL FLUORINE, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE | LEF1, LAS1L, L3MBTL3 | PDE10A 3373/4885ALDH1A1 1806/4885TRPV3 328/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.