Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | FNTA | P49354 | 1/20 | 0.46 |
| ▸ | FNTB | P49356 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12160901 | 0.86 | MEN1 (0.50) | MAPTGAAALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL12160727 | 0.86 | MEN1 (0.50) | MAPTGAAALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL10337750 | 0.75 | MAPT (0.78) | MAPTGAAALDH1A1CYP2C19SMN1; SMN2 | |
| SCHEMBL105931 | 0.75 | MAPT (0.78) | MAPTGAAALDH1A1CYP2C19SMN1; SMN2 | |
| SCHEMBL4613765 | 0.73 | RIPK1 (0.48) | POLBL3MBTL1 | |
| SCHEMBL28486832 | 0.73 | ALDH1A1 (0.59) | ALDH1A1CYP2C9CYP2C19NPC1HTT | |
| Hydrochloric Acid SCHEMBL28482321 | 0.72 | ALDH1A1 (0.58) | ALDH1A1CYP2C9CYP2C19NPC1HTT | |
| SCHEMBL24725073 | 0.72 | MAPT (0.50) | MAPTGAAALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL12160730 | 0.72 | L3MBTL1 (0.47) | MAPTGAAALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL12160900 | 0.72 | L3MBTL1 (0.47) | MAPTGAAALDH1A1CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2411363-A1 | SUBSTITUTED PIPERIDINES AS PAR-1 ANTAGONISTS | Bayer Pharma AG (DE) | 2012-02-01 | — | — | EP | disclosed |