Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 2/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.45 |
| ▸ | UTS2R | Q9UKP6 | 3/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23123430 | 0.88 | RIPK1 (0.50) | RIPK1SIGMAR1UTS2RCNR2POLB | |
| SCHEMBL24700138 | 0.79 | RIPK1 (0.52) | RIPK1CNR2L3MBTL1 | |
| SCHEMBL4776278 | 0.78 | RIPK1 (0.65) | RIPK1HSD11B1 | |
| SCHEMBL28188380 | 0.75 | RIPK1 (0.47) | RIPK1UTS2R | |
| SCHEMBL486204 | 0.73 | MAPT (0.49) | POLBL3MBTL1 | |
| SCHEMBL23139723 | 0.73 | RIPK1 (0.43) | RIPK1UTS2RCNR2HRH3 | |
| SCHEMBL938757 | 0.73 | RIPK1 (0.59) | RIPK1HSD11B1 | |
| SCHEMBL7977029 | 0.73 | HTR1A (0.58) | RIPK1SIGMAR1POLBL3MBTL1 | |
| SCHEMBL23124099 | 0.73 | EPHX2 (0.67) | HRH3 | |
| SCHEMBL25322924 | 0.71 | PRMT5 (0.58) | RIPK1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1910292-A1 | PIPERIDINE DERIVATIVE AS TACHYKININ RECEPTOR ANTAGONIST | Takeda Pharmaceutical Company Limited (JP) | 2008-04-16 | — | — | EP | disclosed |
| WO-2007015588-A1 | PIPERIDINE DERIVATIVE AS TACHYKININ RECEPTOR ANTAGONIST | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-08 | — | — | WO | disclosed |