Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP14 | Q460N5 | 1/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 4/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 4/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 4/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 4/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | EBP | Q15125 | 1/20 | 0.37 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL467514 | 0.79 | NPC1 (0.57) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL29401646 | 0.79 | NPC1 (0.57) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| Hydrochloric Acid SCHEMBL31307094 | 0.77 | NPC1 (0.55) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| Hydrochloric Acid SCHEMBL11234820 | 0.77 | NPC1 (0.55) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL30765432 | 0.75 | MAPT (0.53) | POLBTSHRKMT2ANPC1RAB9A | |
| SCHEMBL1742038 | 0.75 | MAPT (0.53) | POLBTSHRKMT2ANPC1RAB9A | |
| SCHEMBL5563589 | 0.75 | MAOA (0.55) | POLBMEN1PABPC1KMT2ARAB9A | |
| SCHEMBL3355661 | 0.74 | MYC (0.47) | TSHRNPC1RAB9AALDH1A1MYC | |
| Bromide SCHEMBL28994958 | 0.74 | MAPT (0.51) | POLBTSHRKMT2ANPC1RAB9A | |
| SCHEMBL2994615 | 0.73 | SIGMAR1 (0.44) | SIGMAR1MEN1KMT2ARAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0517852-B1 | TRI- AND TETRA-SUBSTITUTED GUANIDINES AND THEIR USE AS EXCITATORY AMINO ACID ANTAGONISTS | OREGON STATE (US) | 2002-07-10 | — | — | EP | claimed |
| US-9121776-B2 | Welding arc apparel with UV or thermochromic activated images | LINCOLN GLOBAL, INC. (US) | 2015-09-01 | — | — | US | disclosed |
| WO-2014053907-A2 | WELDING ARC APPAREL WITH UV OR THERMOCHROMIC ACTIVATED IMAGES | LINCOLN GLOBAL, INC. (US) | 2014-04-10 | — | — | WO | disclosed |
| WO-2014020386-A1 | WELDING ACCESSORY WITH UV OR THERMOCHROMIC ACTIVATED IMAGES; SYSTEM FORAND METHOD OF DETECTING A THRESHOLD TEMPERATURE OF THERMAL RADIATION EXPOSURE DURING WELDING OPERATIONS | LINCOLN GLOBAL, INC. (US) | 2014-02-06 | — | — | WO | disclosed |
| US-20130026150-A1 | WELDING ARC APPAREL WITH UV OR THEMOCHROMIC ACTIVATED IMAGES | LINCOLN GLOBAL, INC. (US) | 2013-01-31 | — | — | US | disclosed |
| US-7462443-B2 | Leuco dye-containing coating compositions | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) | 2008-12-09 | — | — | US | disclosed |
| WO-2005026274-A1 | COATING COMPOSITIONS CONTAINING A LEUCO DYE-AND A DIARYLGUANIDINE DYE | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) | 2005-03-24 | — | — | WO | disclosed |
| US-20050053870-A1 | Leuco dye-containing coating compositions | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. | 2005-03-10 | — | — | US | disclosed |