Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
| ▸ | PTGES2 | Q9H7Z7 | 3/20 | 0.43 |
| ▸ | CA12 | O43570 | 4/20 | 0.42 |
| ▸ | CA2 | P00918 | 4/20 | 0.42 |
| ▸ | CA9 | Q16790 | 4/20 | 0.42 |
| ▸ | LOX | P28300 | 1/20 | 0.42 |
| ▸ | C1S | P09871 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | TTK | P33981 | 2/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | MMP12 | P39900 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14182748 | 0.85 | HTR6 (0.51) | ALDH1A1HTR6CA12CA2CA9 | |
| SCHEMBL18773978 | 0.82 | ALDH1A1 (0.50) | ALDH1A1MAPK1HTR6CA12CA2 | |
| SCHEMBL226516 | 0.79 | HTR6 (0.48) | ALDH1A1HTR6CA12CA2CA9 | |
| SCHEMBL31463126 | 0.76 | LOX (0.60) | ALDH1A1HTR6PTGES2CA12CA2 | |
| SCHEMBL9843436 | 0.76 | LOX (0.60) | ALDH1A1HTR6PTGES2CA12CA2 | |
| SCHEMBL8770103 | 0.74 | KCNH2 (0.49) | ALDH1A1MAPK1CA12CA2CA9 | |
| SCHEMBL17739625 | 0.73 | ALDH1A1 (0.65) | ALDH1A1MAPK1HTR6CA12CA2 | |
| SCHEMBL15458653 | 0.72 | ALDH1A1 (0.79) | ALDH1A1MAPK1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL14067590 | 0.72 | ALDH1A1 (0.79) | ALDH1A1MAPK1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL27681764 | 0.72 | ALDH1A1 (0.79) | ALDH1A1MAPK1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7375176-B2 | Liquid crystal poly(phenylene sulfonic acids) | CASE WESTERN RESERVE UNIVERSITY | 2008-05-20 | — | — | US | disclosed |
| US-20050239994-A1 | Liquid crystal poly(phenylene sulfonic acids) | CASE WESTERN RESERVE UNIVERSITY | 2005-10-27 | — | — | US | disclosed |