SCHEMBL226516

SCHEMBL226516

O=S(=O)(c1ccccc1)c1cc(Br)ccc1Br

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 6/20 0.48
POLB P06746 1/20 0.44
GAA P10253 1/20 0.44
GFER P55789 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.43
PTPRC P08575 1/20 0.41
KMT2A Q03164 2/20 0.41
MEN1 O00255 1/20 0.41
CA1 P00915 2/20 0.41
CA2 P00918 2/20 0.41
CA4 P22748 2/20 0.41
CA6 P23280 2/20 0.41
KDM4E B2RXH2 1/20 0.40
ALDH1A1 P00352 1/20 0.40
CA12 O43570 1/20 0.40
CA3 P07451 1/20 0.40
CA5A P35218 1/20 0.40
CA7 P43166 1/20 0.40
PLA2G7 Q13093 1/20 0.40
CA9 Q16790 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL229081 0.85 HTR6 (0.48) HTR6POLBGAAGFERPTPRC
SCHEMBL12087024 0.81 GAA (0.69) HTR6POLBGAAGFERL3MBTL1
SCHEMBL10655207 0.81 HTR6 (0.52) HTR6KMT2AMEN1CA1CA2
SCHEMBL3833910 0.79 CA1 (0.58) HTR6POLBGAAGFERKMT2A
SCHEMBL4863656 0.79 ALDH1A1 (0.46) HTR6GAAKMT2AMEN1CA1
SCHEMBL14182748 0.78 HTR6 (0.51) HTR6GAAL3MBTL1KMT2AMEN1
SCHEMBL16810 0.78 HSD11B1 (0.57) HTR6POLBGAAGFERCA1
SCHEMBL2350373 0.78 AKR1B1 (0.51) HTR6POLBGAAGFERKMT2A
SCHEMBL10694631 0.77 HTR6 (0.50) HTR6POLBGAAGFERKMT2A
SCHEMBL2472588 0.76 CA2 (0.54) HTR6KMT2ACA1CA2CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2519554-B1 POLYARYLENE POLYMERS AND PROCESSES FOR PREPARING DU PONT (US) 2016-03-16 EP disclosed
US-8609804-B2 Polyarylene polymers and processes for preparing E I DU PONT DE NEMOURS AND COMPANY (US) 2013-12-17 US disclosed
US-20120322973-A1 POLYARYLENE POLYMERS AND PROCESSES FOR PREPARING E I DU PONT DE NEMOURS AND COMPANY (US) 2012-12-20 US disclosed
US-20120322973-A1 POLYARYLENE POLYMERS AND PROCESSES FOR PREPARING E I DU PONT DE NEMOURS AND COMPANY (US) 2012-12-20 US disclosed
US-20120322973-A1 POLYARYLENE POLYMERS AND PROCESSES FOR PREPARING E I DU PONT DE NEMOURS AND COMPANY (US) 2012-12-20 US disclosed
US-20120302725-A1 POLYARYLENE IONOMERS E I DU PONT DE NEMOURS AND COMPANY (US) 2012-11-29 US disclosed
US-20120302725-A1 POLYARYLENE IONOMERS E I DU PONT DE NEMOURS AND COMPANY (US) 2012-11-29 US disclosed
US-20120302725-A1 POLYARYLENE IONOMERS E I DU PONT DE NEMOURS AND COMPANY (US) 2012-11-29 US disclosed
US-20120296065-A1 POLYARYLENE IONOMERS MEMBRANES EI DU PONT DE NEMOURS AND COMPANY (US) 2012-11-22 US disclosed
US-20120296065-A1 POLYARYLENE IONOMERS MEMBRANES EI DU PONT DE NEMOURS AND COMPANY (US) 2012-11-22 US disclosed
US-20120004387-A1 POLYARYLENE POLYMERS AND PROCESSES FOR PREPARING E. I. DU PONT DE NEMOURS AND COMPANY (US) 2012-01-05 US disclosed
WO-2011090705-A2 POLYARYLENE POLYMERS AND PROCESSES FOR PREPARING E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-07-28 WO disclosed
WO-2011090705-A2 POLYARYLENE POLYMERS AND PROCESSES FOR PREPARING E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-07-28 WO disclosed
WO-2011082197-A1 POLYARYLENE IONOMERIC MEMBRANES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-07-07 WO disclosed
WO-2011082197-A1 POLYARYLENE IONOMERIC MEMBRANES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-07-07 WO disclosed
WO-2011082167-A1 METHOD OF MAKING POLYARYLENE IONOMERS AND MEMBRANES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-07-07 WO disclosed
WO-2011082167-A1 METHOD OF MAKING POLYARYLENE IONOMERS AND MEMBRANES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-07-07 WO disclosed
WO-2011082158-A1 POLYARYLENE IONOMERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-07-07 WO disclosed
US-20100105786-A1 Method for Producing Polymer Compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-04-29 US disclosed
EP-1721922-A1 METHOD FOR PRODUCING POLYMER COMPOUND Sumitomo Chemical Company, Limited (JP) 2006-11-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120004387-A1 POLYARYLENE POLYMERS AND PROCESSES FOR PREPARING PCBP1, PARG, PARN HTR6 4302/4885POLB 592/4885GAA 993/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.