Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMP1 | P13497 | 5/20 | 0.56 |
| ▸ | MMP2 | P08253 | 6/20 | 0.56 |
| ▸ | MMP9 | P14780 | 3/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 4/20 | 0.47 |
| ▸ | MMP3 | P08254 | 3/20 | 0.46 |
| ▸ | PDE4A | P27815 | 2/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4864003 | 1.00 | BMP1 (0.56) | BMP1MMP2MMP9HSD17B10NPY5R | |
| SCHEMBL4857259 | 0.90 | NPY5R (0.62) | MMP2MMP9NPY5RALDH1A1 | |
| SCHEMBL4857262 | 0.90 | NPY5R (0.62) | MMP2MMP9NPY5RALDH1A1 | |
| SCHEMBL4858181 | 0.88 | MMP2 (0.56) | BMP1MMP2MMP9NPY5RALDH1A1 | |
| SCHEMBL4858174 | 0.88 | MMP2 (0.56) | BMP1MMP2MMP9NPY5RALDH1A1 | |
| SCHEMBL3740529 | 0.84 | BMP1 (0.51) | BMP1MMP2MMP9HSD17B10NPY5R | |
| SCHEMBL3740536 | 0.84 | BMP1 (0.51) | BMP1MMP2MMP9HSD17B10NPY5R | |
| SCHEMBL3740533 | 0.84 | BMP1 (0.51) | BMP1MMP2MMP9HSD17B10NPY5R | |
| SCHEMBL6021438 | 0.84 | MMP2 (0.63) | BMP1MMP2MMP9HSD17B10POLB | |
| SCHEMBL4865492 | 0.83 | NPY5R (0.45) | BMP1MMP2MMP9NPY5RALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2008520575-A | — | — | 2008-06-19 | — | — | JP | claimed |
| EP-1812012-A2 | PROTEIN TYROSINE PHOSPHATASE INHIBITORS AND METHODS OF USE THEREOF | Ceptyr, Inc. (US) | 2007-08-01 | — | — | EP | claimed |
| WO-2006055525-A2 | PROTEIN TYROSINE PHOSPHATASE INHIBITORS AND METHODS OF USE THEREOF | CEPTYR, INC. (US) | 2006-05-26 | — | — | WO | claimed |