Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | RAB9A | P51151 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | BCHE | P06276 | 1/20 | 0.67 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.66 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.62 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.58 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.58 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27762381 | 0.89 | NPC1 (0.63) | NPC1MAPTRAB9ALMNABCHE | |
| SCHEMBL28126221 | 0.89 | NPC1 (0.63) | NPC1MAPTRAB9ALMNABCHE | |
| SCHEMBL5313684 | 0.89 | NPC1 (0.63) | NPC1MAPTRAB9ALMNABCHE | |
| SCHEMBL28796418 | 0.87 | ABCG2 (0.86) | NPC1MAPTRAB9ALMNABCHE | |
| SCHEMBL1764954 | 0.87 | ABCG2 (0.86) | NPC1MAPTRAB9ALMNABCHE | |
| SCHEMBL31059038 | 0.87 | NPC1 (0.60) | NPC1MAPTRAB9ALMNABCHE | |
| SCHEMBL27632288 | 0.83 | LMNA (0.57) | NPC1MAPTRAB9ALMNABCHE | |
| SCHEMBL7197232 | 0.83 | NPC1 (0.63) | NPC1MAPTRAB9ALMNABCHE | |
| SCHEMBL8146613 | 0.83 | NLRP3 (0.57) | NPC1MAPTRAB9ALMNABCHE | |
| SCHEMBL27923020 | 0.83 | NPC1 (0.63) | NPC1MAPTRAB9ALMNABCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111116535-A | Pseudo-osbeckia chinensis flower extract and application thereof | 海南师范大学 | 2020-05-08 | — | — | CN | claimed |
| CN-107106519-A | Therapeutic agent for human | 伊翁斯制药有限责任公司 | 2017-08-29 | — | — | CN | claimed |
| CN-102081074-B | Quality detection method for 2'-hydroxy-4,4',5',6'-tetramethyl-tetramethoxide chalcone | KUNMING PHARMACEUTICAL CORP | 2013-09-11 | — | — | CN | claimed |
| CN-102267888-A | Chalcone derivative as well as preparation method and application thereof used as inducer in inducing apoptosis of tumor cells | — | 2011-12-07 | — | — | CN | claimed |
| CN-102081074-A | Quality detection method for 2'-hydroxy-4,4',5',6'-tetramethyl-tetramethoxide chalcone | KUNMING PHARMACEUTICAL CORP | 2011-06-01 | — | — | CN | claimed |
| CN-1990482-A | Flavanonol compounds and their production method and use | ZHEJIANG HISUN NATURELITE PHAR (CN) | 2007-07-04 | — | — | CN | claimed |
| EP-0996432-A2 | BIOLOGICALLY ACTIVE 1,3-BIS-AROMATIC-PROP-2-EN-1-ONES, 1,3-BIS-AROMATIC-PROPAN-1-ONES, AND 1,3-BIS-AROMATIC-PROP-2-YN-1-ONES | STATENS SERUMINSTITUT (DK) | 2000-05-03 | — | — | EP | claimed |
| WO-1999000114-A2 | BIOLOGICALLY ACTIVE 1,3-BIS-AROMATIC-PROP-2-EN-1-ONES, 1,3-BIS-AROMATIC-PROPAN-1-ONES, AND 1,3-BIS-AROMATIC-PROP-2-YN-1-ONES | STATENS SERUM INSTITUT (DK) | 1999-01-07 | — | — | WO | claimed |
| US-20250255853-A1 | HUMAN THERAPEUTIC AGENTS | ANKH LIFE SCIENCES LIMITED (IE) | 2025-08-14 | — | — | US | disclosed |
| EP-4429763-A1 | COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS | Yewsavin, Inc. (US) | 2024-09-18 | — | — | EP | disclosed |
| US-20240285592-A1 | HUMAN THERAPEUTIC AGENTS | ANKH LIFE SCIENCES LIMITED (IE) | 2024-08-29 | — | — | US | disclosed |
| US-11951099-B2 | Methods for treating plasma cell neoplasm with human therapeutic agents | ANKH LIFE SCIENCES LIMITED (IE) | 2024-04-09 | — | — | US | disclosed |
| WO-2023086388-A1 | COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS | YewSavin, Inc. (US) | 2023-05-19 | — | — | WO | disclosed |
| US-20220152001-A1 | HUMAN THERAPEUTIC AGENTS | ANKH LIFE SCIENCES LIMITED (IE) | 2022-05-19 | — | — | US | disclosed |
| CN-101448551-A | Use of chalcones for the treatment of viral disorders | JOHNSON & JOHNSON CONSUMER (US) | 2009-06-03 | — | — | CN | disclosed |
| US-7432303-B2 | Chalcone and its analogs as agents for the inhibition of angiogenesis and related disease states | Bowen, J. Phillip (US) | 2008-10-07 | — | — | US | disclosed |
| CN-1990482-A | Flavanonol compounds and their production method and use | ZHEJIANG HISUN NATURELITE PHAR (CN) | 2007-07-04 | — | — | CN | disclosed |
| US-20050148599-A1 | Chalcone and its analogs as agents for the inhibition of angiogenesis and related disease states | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. | 2005-07-07 | — | — | US | disclosed |
| EP-0915864-A1 | GASTROPROTECTIVE FLAVONE/FLAVANONE COMPOUNDS WITH THERAPEUTIC EFFECT ON INFLAMMATORY BOWEL DISEASE | Dong A Pharmaceutical Co. Ltd. (KR) | 1999-05-19 | — | — | EP | disclosed |
| WO-1998004541-A1 | GASTROPROTECTIVE FLAVONE/FLAVANONE COMPOUNDS WITH THERAPEUTIC EFFECT ON INFLAMMATORY BOWEL DISEASE | DONG A PHARMACEUTICAL CO., LTD. (KR) | 1998-02-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11951099-B2 | Methods for treating plasma cell neoplasm with human therapeutic agents | MCL1, CD44, INMT | NPC1 518/4885MAPT 1097/4885RAB9A 2714/4885 |
| US-20240285592-A1 | HUMAN THERAPEUTIC AGENTS | INMT, NLN, MYC | NPC1 926/4885MAPT 143/4885RAB9A 3068/4885 |
| US-20050148599-A1 | Chalcone and its analogs as agents for the inhibition of angiogenesis and related disease states | FLT1, VEGFA, FLT4 | NPC1 1134/4885MAPT 341/4885RAB9A 2231/4885 |
| US-20220152001-A1 | HUMAN THERAPEUTIC AGENTS | INMT, HNMT, HASPIN | NPC1 1517/4885MAPT 497/4885RAB9A 2823/4885 |
| US-20250255853-A1 | HUMAN THERAPEUTIC AGENTS | HASPIN, TIPARP, SHARPIN | NPC1 2233/4885MAPT 1131/4885RAB9A 1880/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.