Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | KDM4A | O75164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4864204 | 1.00 | KMT2A (0.49) | KMT2ACYP2D6CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL4866881 | 0.86 | KMT2A (0.45) | KMT2ACYP2D6CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL4866880 | 0.86 | KMT2A (0.45) | KMT2ACYP2D6CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL4857262 | 0.84 | NPY5R (0.62) | ALDH1A1MAPTNPY5R | |
| SCHEMBL4857259 | 0.84 | NPY5R (0.62) | ALDH1A1MAPTNPY5R | |
| SCHEMBL4866934 | 0.83 | GRIA1 (0.46) | KMT2ACYP2D6CYP2C9CYP2C19MMP8 | |
| SCHEMBL4866943 | 0.83 | GRIA1 (0.46) | KMT2ACYP2D6CYP2C9CYP2C19MMP8 | |
| SCHEMBL4858174 | 0.82 | MMP2 (0.56) | ALDH1A1MAPTNPY5RCNR1 | |
| SCHEMBL4858181 | 0.82 | MMP2 (0.56) | ALDH1A1MAPTNPY5RCNR1 | |
| SCHEMBL3738146 | 0.81 | PTPN1 (0.49) | KMT2ACYP2D6CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2008520575-A | — | — | 2008-06-19 | — | — | JP | claimed |
| EP-1812012-A2 | PROTEIN TYROSINE PHOSPHATASE INHIBITORS AND METHODS OF USE THEREOF | Ceptyr, Inc. (US) | 2007-08-01 | — | — | EP | claimed |
| WO-2006055525-A2 | PROTEIN TYROSINE PHOSPHATASE INHIBITORS AND METHODS OF USE THEREOF | CEPTYR, INC. (US) | 2006-05-26 | — | — | WO | claimed |