Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | CRHBP | P24387 | 2/20 | 0.52 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4856346 | 0.94 | HTT (0.53) | MEN1KMT2AMAPTCRHBPCRHR2 | |
| SCHEMBL6607465 | 0.90 | KMT2A (0.57) | MEN1KMT2ACRHBPCRHR2TDP1 | |
| SCHEMBL6677228 | 0.79 | RAB9A (0.51) | MEN1KMT2AMAPTCRHBPCRHR2 | |
| SCHEMBL6681877 | 0.78 | GNRHR (0.49) | MEN1KMT2AMAPTCRHBPCRHR2 | |
| SCHEMBL2835652 | 0.77 | MAPT (0.57) | MEN1KMT2AMAPTCRHBPCRHR2 | |
| SCHEMBL6675975 | 0.76 | NQO2 (0.48) | MEN1KMT2AMAPTCRHBPCRHR2 | |
| Hydrochloric Acid SCHEMBL7563670 | 0.76 | MAPT (0.56) | MEN1KMT2AMAPTCRHBPCRHR2 | |
| SCHEMBL11193465 | 0.76 | NQO2 (0.48) | MEN1KMT2AMAPTCRHBPCRHR2 | |
| SCHEMBL11192327 | 0.76 | ALDH1A1 (0.50) | MEN1KMT2AMAPTTDP1ALDH1A1 | |
| SCHEMBL8460016 | 0.76 | MTNR1A (0.50) | MEN1KMT2AMAPTTDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7384963-B2 | 2′-Methyl-5-(1,3,4-oxadiazol-2-yl)1, 1′-biphenyl-4-carboxaide derivatives and their use as p38 kinase | GLAXO GROUP LIMITED (GB) | 2008-06-10 | — | — | US | disclosed |