Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL775818 | 0.78 | SMN1; SMN2 (0.35) | SMN1; SMN2 | |
| SCHEMBL21623615 | 0.77 | MMP8 (0.31) | — | |
| SCHEMBL7434659 | 0.76 | SMN1; SMN2 (0.50) | SMN1; SMN2 | |
| SCHEMBL13798757 | 0.76 | SMN1; SMN2 (0.50) | SMN1; SMN2 | |
| SCHEMBL3147895 | 0.76 | SMN1; SMN2 (0.33) | SMN1; SMN2 | |
| SCHEMBL12027691 | 0.74 | CA1 (0.39) | SMN1; SMN2 | |
| SCHEMBL6633558 | 0.74 | SMN1; SMN2 (0.32) | SMN1; SMN2 | |
| SCHEMBL29187423 | 0.74 | SMN1; SMN2 (0.32) | SMN1; SMN2 | |
| SCHEMBL1629957 | 0.74 | DPP4 (0.32) | SMN1; SMN2 | |
| SCHEMBL13537883 | 0.74 | TSHR (0.43) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7439266-B2 | Malononitrile compound and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2008-10-21 | — | — | US | disclosed |
| US-20060004092-A1 | Malononitrile compound and use thereof pesticides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2006-01-05 | — | — | US | disclosed |
| WO-2004020399-A1 | MALONONITRILE COMPOUND AND USE THEREOF AS PESTICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2004-03-11 | — | — | WO | disclosed |
| US-6066633-A | PREVENT TISSUE DEGRADATION | ADIR ET COMPAGNIE (FR) | 2000-05-23 | — | — | US | disclosed |
| US-4906635-A | Carboxyalkyl dipeptides as antiglaucoma agents | SCHERING CORPORATION (US) | 1990-03-06 | — | — | US | disclosed |
| EP-0195817-A1 | CARBOXYALKYLDIPEPTIDES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM. | SCHERING CORP (US) | 1986-10-01 | — | — | EP | disclosed |
| WO-1986001803-A1 | CARBOXYALKYLDIPEPTIDES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SCHERING CORPORATION (US) | 1986-03-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060004092-A1 | Malononitrile compound and use thereof pesticides | ME1, MAL2, ME3 | SMN1; SMN2 1749/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.